捕集离子淌度谱 ( TIMS ) 技术提供了额外的分离维度，加速了从 4D-Omics 到 MALDI 成像的各种研究应用。布鲁克 timsTOF 质谱仪由 PASEF® 平行累积连续碎裂技术提供动力，提升了速度和灵敏度，用于鉴定和定量具有挑战性的化合物。

Trapped ion mobility spectrometry (TIMS) provides an additional dimension of separation, accelerating diverse research applications from 4D-Omics to MALDI Imaging. Powered by Parallel Accumulation Serial Fragmentation (PASEF®), Bruker’s timsTOF instruments offer next generation speed and sensitivity to identify and quantify challenging ...

timsTOF Pro 2 配备了最新一代双 TIMS 分析器，离子容量可提高三倍。 经过简化的离子透镜最大限度地提高了离子传输效率和灵敏度，为 4D- 多组学建立了新的标准。

TimsTOF Pro 2 由新一代平行累积连续碎裂技术（ PASEF® ）所驱动，为 4D- 多组学的应用和发展拓宽了道路。 其久经考验的稳健性、高灵敏度以及超快速的二级采集速率，使得 TimsTOF Pro 2 作为分析平台，成为 4D- 蛋白质组学、4D- 代谢组学以及 4D- 脂质组学研究的不二 ...

The timsTOF HT yielded over 2-fold more reproducible precursors (triplicate LC–MS injections, CV < 20%) compared to timsTOF Pro 2. Additionally, timsTOF HT generally showed improved quantitative capabilities when ≥300 or ≥600 ng peptide mass of neat or Proteograph plasma, respectively, was analyzed.

timsTOF Pro 2 由最新一代平行累积连续碎裂技术（ PASEF ® ）所驱动，为 4D- 多组学的应用和发展拓宽了道路。其久经考验的稳健性、高灵敏度以及超快速的二级采集速率，使得 timsTOF Pro 2 作为分析平台，成为蛋白质组学研究的不二选择！

timsTOF was engineered by Bruker experts as an open platform to accelerate the adoption of ion mobility mass spectrometry analysis across all applications. Providing consistently high ion mobility resolution, timsTOF unravels the complexity of samples and unlocks insights that remain hidden in standard mass spectrometry.

2021年4月2日 · OpenTIMS is a C++ library capable of reading Bruker TDF files. It opens up Bruker's proprietary codebase. TimsPy and TimsR build on top of OpenTIMS, enabling swift and user-friendly data access to the raw data with Python and R.

timsTOF Pro 2由最新一代平行累积连续碎裂技术 (Parallel Accumulation Serial Fragmentation, PASEF®) 所驱动，为 4D-多组学 的应用和发展拓宽了道路。 其久经考验的稳健性、高灵敏度以及超快速的二级采集速率，使得 timsTOF Pro 2作为分析平台，成为 4D-蛋白质组学 、 4D-代谢组学 ...

Unleash 4D-Proteomics™ with the timsTOF Ultra 2 – the ultimate fusion of trapped ion mobility spectrometry (TIMS) with quadrupole time-of-flight (QTOF) technology. TIMS PASEF ® mode parallelization captures ions with near 100% efficiency, delivering exceptional sensitivity and unparalleled proteome depth at 300 Hz speeds.