Thiophene is a heterocyclic compound with the formula C 4 H 4 S. Consisting of a planar five-membered ring, it is aromatic as indicated by its extensive substitution reactions. It is a colorless liquid with a benzene -like odor. In most of its reactions, it resembles benzene.

噻 ㄙㄞ 吩 （吩咐的吩） （英語： Thiophene）是 雜環化合物， 化學式 C 4 H 4 S。 由平面五元環組成，其廣泛的取代反應表明它有 芳香性。 它是無色液體，氣味似 苯。 在其大部分反應中都類似苯。 噻吩最初是作為苯的雜質而發現的。 [1] 靛紅 與硫酸、粗苯混合形成一種藍色染料，早期認為這是苯的反應，直到德國化學家 維克托·梅耶 分離出噻吩，才發現了這種雜環化合物的存在。 [2] 噻吩天然存在於石油、煤焦油和頁岩油中，在石油中含量可高達數個百分點，所以石油精煉中 …

Thiophene is a monocyclic heteroarene that is furan in which the oxygen atom is replaced by a sulfur. It has a role as a non-polar solvent. It is a mancude organic heteromonocyclic parent, a member of thiophenes, a monocyclic heteroarene and a volatile organic compound.

thiophene, the simplest sulfur-containing aromatic compound, with molecular formula C 4 H 4 S, which closely resembles benzene in its chemical and physical properties. It occurs with benzene in coal tar, from which source it was first isolated in 1883. Today, thiophene is prepared commercially from butane or butene and sulfur or sulfur dioxide.

Thiophene is a heterocyclic compound of particular interest in the field of organic chemistry. This cyclic molecule, sometimes referred to as thiofuran, consists of four carbon atoms and one sulfur atom in a ring structure. It is an analog to the compound benzene, where one CH 2 group in the benzene ring is replaced with sulfur.

2025年2月27日 · Thiophene is five-member heterocyclic compounds containing a sulfur atom and is presented at coal tar crude benzene at small amounts. It is a kind of colorless liquid having similar order as benzene aromatic with the boiling point being 84 °C.

2024年4月22日 · Thiophene is an electron-rich aromatic compound. Its resonance energy is approximately equal to that of pyrrole, and much higher than that of furan. It is found in nature in certain plant products, and is a component of many pharmaceuticals and synthetic dyes.

2007年1月1日 · Thiophene is a useful template for four-carbon homologation via reduction, as well as a bioisostere of the benzene ring and other heterocycles in medicinal chemistry. Thiophene is a π-electron-excessive heterocycle.

Thiophene is a heterocyclic compound consisting of a planar five-membered ring that improves the photovoltaic performance of dye-sensitized solar cells (DSSCs) (Hara et al., 2005; Dentani et al., 2009; Zhang et al., 2009; Kim et al., 2012; Naka et al., 2016; Imae et al., 2015) [1–6].

Thiophene is a privileged pharmacophore in medicinal chemistry owing to its diversified biological attributes. The thiophene moiety has been ranked 4th in the US FDA drug approval of small drug molecules, with around 7 drug approvals over the last decade. The present review covers USFDA-approved drugs possessing a thiophene ring system.