TEPADINA is an alkylating drug indicated: To reduce the risk of graft rejection when used in conjunction with high-dose busulfan and cyclophosphamide as a preparative regimen for allogeneic hematopoietic progenitor (stem) cell transplantation (HSCT) for pediatric patients with class 3 beta-thalassemia.

2020年3月27日 · TEPADINA (thiotepa) is an alkylating drug indicated: To reduce the risk of graft rejection when used in conjunction with high-dose busulfan and cyclophosphamide as a preparative regimen for allogeneic hematopoietic progenitor (stem) cell transplantation (HSCT) for pediatric patients with class 3 beta-thalassemia. (1.1, 14)

商品名：Tepadina. 中文名：塞替派冻干粉注射剂. 临床应用. 主要用于治疗乳腺癌、卵巢癌、膀胱癌(局部灌注)及癌性体腔积液(腔内注射)等，也曾用于治疗原发性肝癌、子宫颈癌、黑色素瘤、胃肠道肿瘤等。 药理

TEPADINA (thiotepa) is an alkylating drug indicated: To reduce the risk of graft rejection when used in conjunction with high-dose busulfan and cyclophosphamide as a preparative regimen for...

Tepadina is a powder that is made up into a solution for infusion (drip into a vein). It contains the thiotepa. What is Tepadina used for? as a ‘conditioning’ (preparative) treatment before transplantation of haematopoietic progenitor cells (the cells that make blood cells).

Thiotepa is a reactive compound that, under acidic, neutral, or alkaline conditions, undergoes solvolysis, leading to potential side reactions such as polymerization and dimerization into piperazines. During acidic degradation, thiotepa reacts with chloride ions to produce monochloro, dichloro, and trichloro derivatives.

塞替派（tepadina）可以有效治疗卵巢癌，适用于卵巢癌非根治术后/腹腔播散伴有腹水/小骨分转移/肺转移伴有胸水等，并且该药品治疗卵巢癌的有效率可达40％。

2022年1月10日 · 塞替派(Tepadina)是一种合成的抗肿瘤药，是乙烯亚胺类烷化剂的代表，主要用于治疗卵巢癌、乳腺癌、膀胱癌和消化道癌，同时还适用于成人和儿童患者自体或同种基因造血祖细胞移植前的预处理。

2023年7月27日 · Thiotepa (Thioplex®, Tepadina®) is an alkylating agent used in the treatment of specific types of breast, ovarian, bladder, and lymphoma cancers, among others.

Tepadina is used to treat cancer of the breast, ovary, bladder, and certain body cavities. Tepadina may also be used for purposes not listed in this medication guide. Get emergency medical help if you have signs of an allergic reaction: hives; wheezing, difficult breathing; swelling of your face, lips, tongue, or throat.