Tafia (also called guildive) is a drink similar to rum made from sugarcane juice. [1] It is typically unaged whereas rum is typically aged in wooden barrels to reduce the level of fusel. Most of the fusel is absorbed in the first two years. Premium rums are aged for a longer period, incidentally increasing the evaporation of ethanol.

Thirdly, at the level of the blood clot by activated TAFI (TAFIa), a zinc-dependent metallocarboxypeptidase that removes the C-terminal lysines from the partially degraded fibrin clot and thereby abrogates the fibrin cofactor function in plasminogen activation (reviewed in [9,10]). As TAFI is being activated by thrombin, the key component of ...

2016年5月24日 · TAFIa is a carboxypeptidase that cleaves carboxyl terminal lysine and arginine residues from protein and peptide substrates, including plasminogen-binding sites on cell surface receptors. Carboxyl terminal lysine residues play a pivotal role in enhancing cell surface plasminogen activation to plasmin.

2015年3月20日 · tafia 的活性是在 tafi 被凝血酶- tm激活后, 用 furoylacroleyl 丙氨酰- 精氨酸作为底物, 测定其在 336 nm处吸收光谱的改变,可测定 TAFIa 的总量

Tafia (30 years of age) is a native of Haitian-American North Miami, Florida. He is a rapper, songwriter and Creative director. He understands the necessity of grinding within the music industry and this reflects in His new EP “Street Fanci 3" an 11 song project, featuring his popular single “Uber Me”.

TAFIa (18.15 nmol/L), with or without PTCI (20 μmol/L) or εACA (20 mmol/L) were also tested to verify lysine-dependence of plasminogen and t-PA binding. The binding was quantified using flow cytometry and the values are expressed as GMFI after normalization using the background values obtained from resting platelets.

2000年12月1日 · TAFI (58 kDa) activation is catalyzed by plasmin, 18 27 trypsin, 18 and thrombin, 18 28 appearing to require cleavage at Arg92 to yield a 92–amino acid activation peptide of ≈15 kDa and a 309–amino acid enzyme (TAFIa) of 35 kDa (Figure 1). 18 TAFIa exhibits at least a 10-fold reduced affinity for plasminogen, suggesting that binding to ...

2006年9月7日 · TAFI is activated by thrombin generated via the extrinsic pathway (high tissue factor), intrinsic pathway (low tissue factor), or in the presence of thrombomodulin (TM). TAFIa protects the fibrin clot by inhibition of tPA-mediated fibrinolysis.

DS-1040 Tosylate 是一种具有口服活性的，选择性的凝血酶可激活的纤维蛋白溶解抑制剂 (TAFIa) 的抑制剂，对人和大鼠 TAFIa 的 IC 50 分别为 5.92 nM 和 8.01 nM。DS-1040 Tosylate 是纤维蛋白溶解增强剂，可用于血栓栓塞性疾病。

Since activated thrombin-activatable fibrinolysis inhibitor (TAFIa) was discovered in 1988, considerable interest has developed in the biological role of this enzyme, particularly in hemostasis and thrombotic diseases.