TRAF3-interacting JNK-activating modulator is a protein that in humans is encoded by the TRAF3IP3 gene. [5][6]

结果表明，HECTD3介导TRAF3泛素化修饰主要是通过泛素K63处进行多聚泛素化修饰，促进 I型IFN 的产生。 确定了泛素修饰的类型（单筛），下一步还需确定TRAF3是怎么被泛素化修饰 …

2025年3月30日 · TRAF3IP3 (TRAF3 Interacting Protein 3) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor …

2025年3月30日 · TRAF3 (TNF Receptor Associated Factor 3) is a Protein Coding gene. Diseases associated with TRAF3 include Immunodeficiency 132A and Immunodeficiency 132B. Among …

2023年7月21日 · Here, we found that ablation of TRAF3 increased M1 markers, iNOS, FGR and SLC4A7, while down-regulated M2 markers, CD206, CD36 and ABCC3, expression levels in …

2025年3月11日 · Through IP-MS analysis, STRN3 is identified as a direct downstream interactor with TRAF3IP3 and corroborated to regulate ER stress positively. Mechanistically, TRAF3IP3 …

目前在哺乳动物中发现6个肿瘤坏死因子受体作用因子（TNF receptor associated factors，TRAFs）家族成员，它们主要参与TNF受体家族信号通路.

2022年9月27日 · Here, we found that tumor necrosis factor receptor (TNFR)–associated factor 3 (TRAF3) enhanced the activation of JAK1 and STAT1 specifically in CD4 + T cells by …

2016年3月30日 · Therefore, our findings delineated a new function for iOPN to act as a positive regulator in innate antiviral immunity through stabilization of TRAF3. The innate immunity is …

2024年10月1日 · TRAF3 promoted STAT6 activation by regulating recruitment of the inhibitory molecule protein tyrosine phosphatase 1B to the IL-4R signaling complex, in a manner that …