TPT falls broadly into three categories: (i) isoniazid monotherapy for 6 or 9 months (6H or 9H), (ii) rifamycin-based shorter treatment and (iii) Lfx for 6 months (6Lfx) for people exposed to MDR/ RR-TB.

In children and adolescents between 3 months and 16 years of age with non-severe TB (without suspicion or evidence of MDR/RR-TB), a 4-month treatment regimen (2HRZ (E)/2HR) should be used. (Strong recommendation, moderate certainty of evidence) – new recommendation.

TPT will treat the TB infection early on and can prevent the bacteria from multiplying and causing disease. These medicines are well-tolerated by most people and any adverse drug reactions that emerge

TPT has been shown to be effective at preventing TB in PLHIV and should be considered part of a comprehensive HIV treatment plan. This TB Preventive Treatment Implementation Guide and Toolkit is intended for use by PEPFAR teams and implementing partners who support the programmatic scale-up and improvement of TPT for PLHIV.

2HRZ(E)/2HR regimen As in adults, TB treatment in children and adolescents includes an intensive phase of 2 months followed by a continuation phase of 2–4 months. In the intensive phase, tubercle bacilli are rapidly killed to prevent disease progression and transmission, and the development of drug-resistance. In

2024年6月1日 · This multicenter randomized controlled trial compared the effectiveness of a shortened four-month regimen of treatment (2HRZ/2HR or 2HRZE/2HR) with the previous standard six-month regimen (2HRZ/4HR or 2HRZE/4HR) in children under 16 …

2022年2月3日 · TPT merupakan salah satu langkah untuk mencegah orang ILTB yang berisiko untuk berkembang menjadi sakit TBC positif. Tujuan pemberian TPT adalah untuk mencegah terjadinya sakit TBC sehingga dapat menurunkan beban TBC. Secara spesifik, yuk kita lihat siapa saja yang bisa diberikan TPT?

2024年7月11日 · Supplemental Guidelines to the OHG on Implementation of 2HRZE/2HR Treatment Regimen for 3 months to 16 years of age with Non-severe Drug-susceptible DS-TB (Department Circular No. 2024-0211 & 2024-0211_A)

Supplemental Guidelines to the OHG on Implementation of 2HRZE/2HR Treatment Regimen for 3 months to 16 years of age with Non-severe Drug-susceptible DS-TB (Department Circular No. 2024-0211 & 2024-0211_A) 865.61 KB 639 downloads

2021年8月16日 · Ada dua pilihan utama untuk TPT yaitu: paduan 6H (Isoniazid) dan 3HP (Isoniazid/Rifapentine). Paduan 6H adalah: paduan isoniazid (INH) yang diberikan selama 6 bulan dan dikonsumsi satu kali sehari. Paduan 3HP adalah: paduan TPT jangka pendek.