2024年12月25日 · TPH1 (Tryptophan Hydroxylase 1) is a Protein Coding gene. Diseases associated with TPH1 include Bipolar Disorder and Personality Disorder. Among its related …

Tryptophan hydroxylase 1 (TPH1) is an isoenzyme of tryptophan hydroxylase which in humans is encoded by the TPH1 gene. [5] TPH1 was first discovered to support serotonin synthesis in …

This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important …

2025年2月8日 · Gene target information for TPH1 - tryptophan hydroxylase 1 (human). Find diseases associated with this biological target and compounds tested against it in bioassay …

Tryptophan hydroxylase (TPH) is the rate-limiting enzyme in the synthesis of serotonin (5-HT); it converts the amino-acid tryptophan to 5-hydroxy-tryptophan, which is then decarboxylated into …

This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important …

1995年2月24日 · We report the isolation and the organization of the gene encoding human tryptophan hydroxylase (TPH) and an analysis of the corresponding mRNAs. The gene spans …

Recently, two enzymes—TPH1 and TPH2—were reported to form the TPH family in vertebrates and to play divergent roles in serotonergic systems. Here, we examined the evolution of the …

This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important …

编码的蛋白质是两种催化血清素生物合成中的第一个和限速步骤的色氨酸羟化酶之一。 这个基因在外周器官中表达，而色氨酸羟化酶2在神经元中表达。 编码的蛋白质参与低氧诱导的肺压力和 …