TNF-α即肿瘤坏死因子α，也被称作cachectin和TNFSF1A，是TNF超家族的配体。 它是一种多效细胞分子，在炎症、细胞凋亡和免疫系统发育中起着核心作用。 TNF-α由巨噬细胞、单核细胞、中性粒细胞、CD4 +T细胞、NK细胞…

肿瘤坏死因子 ( tumor necrosis factor，TNF )是由巨噬细胞分泌的一种小分子蛋白，正常人血清为4.3±2.8 mg/L。 TNF-α 主要由单核—巨噬细胞分泌； TNF-β 主要由活化的 T淋巴细胞 分泌。

肿瘤坏死因子（TNF）旧称肿瘤坏死因子-α（TNF-α） [1] 以区别肿瘤坏死因子-β，属肿瘤坏死因子超家族一员，是一种涉及到系统性炎症的细胞因子，同时也是属于引起 急相反应 （ 英语 ： Acute-phase protein ） 的众多细胞因子中的一员。

Tumor necrosis factor (TNF), formerly known as TNF-α, is a chemical messenger produced by the immune system that induces inflammation. [5] TNF is produced primarily by activated macrophages, and induces inflammation by binding to its receptors on other cells. [6]

与il-1β相似，tnf-α是一种多效性促炎细胞因子，属于tnf配体超家族。 TNF-α在调节多种发育和免疫过程中发挥着不同的作用，包括炎症、分化、脂质代谢和凋亡，与多种疾病有关。

2021年3月8日 · Tumor necrosis factor alpha (TNF-α) was initially recognized as a factor that causes the necrosis of tumors, but it has been recently identified to have additional important functions as a pathological component of autoimmune diseases. TNF-α binds to two different receptors, which initiate signal tr …

α肿瘤坏死因子（tnf α）是一种主要由巨噬细胞和单核细胞产生的促炎细胞因子，并参与正常炎症反应和免疫反应。 α肿瘤坏死因子在许多病理状态下产生增多，包括败血症、恶性肿瘤、心脏衰竭和慢性炎性疾病。

TNF alpha是一种炎症细胞因子，在急性免疫反应期间由单核细胞和巨噬细胞产生。 TNF alpha与TNFR-1和TNFR-2相互作用，两者都属于TNF受体超家族。 TNF alpha可以促进细胞增殖、分化、细胞因子产生、细胞凋亡或坏死。 TNF alpha可通过与IL1 beta和IL6的协同作用促进血管生成。

Tumour necrosis factor-alpha (TNF-α) is naturally produced by activated macrophages and monocytes. TNF-α is a major regulator of inflammatory responses and is involved in the pathogenesis of some inflammatory and autoimmune diseases.

Tumor Necrosis Factor Alpha (TNF-α) is a cytokine that acts as an arbitrator of the local tissue environment following injury, and is involved in bone tissue regeneration. It can initiate apoptosis and regulate cell survival and proliferation.