TMC-310911 (also known as ASC-09) is an antiviral drug which was originally researched as a treatment for HIV/AIDS. It is a protease inhibitor related to darunavir .

TMC207 is a first-in-class diarylquinoline compound with a novel mechanism of action, the inhibition of bacterial ATP synthase, and potent activity against drug-sensitive and drug …

TMC-310911 (also known as ASC-09) is a novel investigational protease inhibitor (PI) that is structurally similar to the currently available darunavir. It is being investigated for use in HIV-1 …

Recently completed and ongoing studies involving major drug classes against drug-susceptible (DS-) and drug-resistant (DR-) TB, including multidrug resistant (MDR) and extensively drug …

Bedaquiline, formerly TMC207, is a new diarylquinoline antibiotic with specific activity against Mycobacterium tuberculosis and several nontuberculous mycobacteria. It acts by inhibiting …

2008年3月1日 · Basic biology information Drug target/mechanism: TMC-207 (R207910, TMC) is a first-in-class diarylquinone, distinct from any marketed compounds. The compound, identified …

The Global Alliance for TB Drug Development and Tibotec have joined forces to develop a potential first-in-class drug for both drug-susceptible and drug-resistant tuberculosis.

2011年9月9日 · TMC207 (TMC, J) is a novel diarylquinoline ATP synthase inhibitor with potent in vitro activity against M. tuberculosis, including strains resistant to commonly used first- and …

TMC Pill - white oval, 12mm . Generic Name: etravirine. Pill with imprint TMC is White, Oval and has been identified as Intelence 25 mg. It is supplied by Janssen Pharmaceuticals, Inc. …

For drug-susceptible TB, although the current four-drug regimen (isoniazid, rifampin, ethambutol and pyrazinamide) is effective in most cases, the treatment takes 6–9 months because the...