Formation of memory assemblies through the DNA-sensing TLR9 …
Mar 27, 2024 · We demonstrate a novel cascade of learning-induced molecular events in discrete neuronal clusters undergoing dsDNA damage and TLR9-mediated repair, resulting in their …
TLR9 Gene - GeneCards | TLR9 Protein | TLR9 Antibody
Mar 30, 2025 · TLR9 (Toll Like Receptor 9) is a Protein Coding gene. Diseases associated with TLR9 include Cervicitis and Aspergillosis. Among its related pathways are Toll Like Receptor …
Surface toll-like receptor 9 on immune cells and its …
Toll like receptor 9 (TLR9) has been considered as a crucial intracellular pattern recognition receptor in the immune system, which can directly or indirectly mediate innate and adaptive …
Toll-like receptor 9 agonists and combination therapies ... - Nature
Jul 28, 2022 · Toll-like receptor 9 (TLR9) agonists have been extensively investigated as therapeutics in monotherapy or combination therapies for the treatment of cancer, infectious …
Cyclical palmitoylation regulates TLR9 signalling and systemic ...
Jan 2, 2024 · Here, we report that palmitoyl-protein thioesterase 1 (PPT1) regulates systemic autoimmunity by removing S-palmitoylation from TLR9 in lysosomes. PPT1 promotes the …
TLR9 - an overview | ScienceDirect Topics
TLR9 is a receptor that recognizes specific DNA motifs found in both bacterial and viral DNA, and has the potential to be targeted for adjuvants. Recent studies suggest that TLR9 may play a …
TLR9 as a key receptor for the recognition of DNA - PubMed
Apr 29, 2008 · Unmethylated DNA with CpG-motifs is recognized by Toll-like receptor 9 (TLR9) and pleiotropic immune responses are elicited. Macrophages and conventional dendritic cells …
54106 - Gene ResultTLR9 toll like receptor 9 [ (human)]
Feb 8, 2025 · Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence- and pH-dependent manner. Diminished expression and function of TLR9 is a likely consequence of …
TLR9: A friend or a foe - ScienceDirect
Oct 15, 2022 · Toll like receptor 9 (TLR9) is an intracellular TLR, expressed in different immunological and non-immunological cells. Release of cellular components, such as …
The Biology of Toll-Like Receptor 9 and Its Role in Cancer
This review summarizes the current state of knowledge regarding TLR9 features, isoforms, structure, ligands, and signaling, and discusses the roles of TLR9 in cancer pathogenesis.
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