THP-1 is a human monocytic cell line derived from an acute monocytic leukemia patient. It is used to test leukemia cell lines in immunocytochemical analysis of protein-protein interactions, and immunohistochemistry. [1]

THP-1 is a suspension cell line isolated from peripheral blood of an acute monocytic leukemia patient. Depending on culture conditions, these cells can differentiate into macrophages and dendritic cells.

Establishment and characterization of a human acute monocytic leukemia cell line (THP-1). Induction of maturation in cultured human monocytic leukemia cells by a phorbol diester. Lineage infidelity of a human myelogenous leukemia cell line. Isoenzyme studies in human leukemia-lymphoma cell lines -- 1 carboxylic esterase.

THP-1细胞为悬浮细胞，相比于ML-2、HL-60、U937等白血病细胞系，THP-1细胞具有更接近于人原代单核细胞的形态和功能特征（包括细胞分化标记）。 并且相对于人外周血单核细胞（PBMC），THP-1更易在实验室中培养和扩增，且具有更稳定的基因背景，不存在PBMC的个体差异性问题，利于实验结果的重现。 因此，THP-1是各大实验室常用的急性单核细胞白血病细 …

THP1 cells, a spontaneously immortalized monocyte-like cell line derived from the peripheral blood of a 1-year-old monocytic leukemia patient, serve as a critical model in immunological and cancer research.

Originating from a spontaneously immortalized human monocyte-like cell line that naturally expresses many pattern-recognition and cytokine receptors, ATCC THP-1 LUC2 cells represent the most physiologically relevant model to aid advancements in immuno-oncology and …

2016年11月18日 · THP-1 cells, including their genetically engineered derivatives, represent valuable tools for investigating monocyte structure and function in both health and disease.

2024年9月6日 · THP-1 cells are a human monocytic leukemia cell line established by Tsuchiya et al. in 1980. Originating from the blood of a patient with acute monocytic leukemia, these cells have the capacity to differentiate into various types of macrophages and are commonly used in research across multiple fields.

THP-1 is a human monocytic cell line originally isolated from a 1-year old male subject with acute monocytic leukemia (Tsuchiya et al., 1980). The cells are easy to culture and...

THP-1 is a Human acute monocytic leukemia cell line Established from the peripheral blood of a 1-year-old boy with acute monocytic leukemia