2025年3月30日 · THBS1 (Thrombospondin 1) is a Protein Coding gene. Diseases associated with THBS1 include Thrombotic Thrombocytopenic Purpura and Autism Spectrum Disorder. …

Thrombospondin-1 is a secreted protein that acts in the tumor microenvironment to inhibit angiogenesis, regulate antitumor immunity, stimulate tumor cell migration, and regulate the …

Thrombospondin 1 (THBS1) is an endogenous inhibitor of angiogenesis, but it also promotes tumor invasion, metastasis, and immune response in the tumor environment. Previous …

2023年9月25日 · Bone marrow-derived monocyte-like cells recruited by CXCL12 are the primary source of THBS1, which contributes to the development of metastasis by inducing cytotoxic T …

2021年6月24日 · Here we show that Thbs1, but not Thbs2, Thbs3 or Thbs4, induces lethal cardiac atrophy when overexpressed. Mechanistically, Thbs1 binds and activates the …

Thrombospondin-1 Regulates Trophoblast Necroptosis via NEDD4-Mediated Ubiquitination of TAK1 in Preeclampsia. The role of THBS1 and PDGFD in the immune microenvironment of …

2025年2月9日 · Title: The role of THBS1 and PDGFD in the immune microenvironment of Helicobacter pylori-associated gastric cancer. CircTHBS1 promotes trophoblast cell migration …

2025年1月3日 · Deletion of Thbs1 (Thbs1 KO) suppressed HSC inflammaging and restored clinically relevant defects associated with hematopoietic aging including loss of HSC self …

2024年4月28日 · Here, we report that skeletal muscle-specific thrombospondin-1 transgenic mice (Thbs1 Tg) have profound muscle atrophy with age-dependent decreases in exercise capacity …

2023年12月3日 · Clinical resource with information about THBS1, and available tests. There are links to practice guidelines and authoritative resources like GeneReviews, PubMed, …