TCF4 - Wikipedia
TCF4 is primarily involved in neurological development of the fetus during pregnancy by initiating neural differentiation by binding to DNA. It is found in the central nervous system, somites, and …
TCF4 Gene - GeneCards | ITF2 Protein | ITF2 Antibody
Mar 30, 2025 · TCF4 (Transcription Factor 4) is a Protein Coding gene. Diseases associated with TCF4 include Pitt-Hopkins Syndrome and Corneal Dystrophy, Fuchs Endothelial, 3. Among its …
The molecular properties of the bHLH TCF4 protein as an …
Mar 27, 2025 · Background Transcription factor 4 (TCF4) is a member of the basic helix-loop-helix (bHLH) family of transcription factors that guides proper embryogenesis, particularly …
Transcription factor TCF4: structure, function, and associated …
TCF4 encodes a transcription factor containing a basic helix-loop-helix structural motif (bHLH). The proteins of this group contain a DNAbinding domain and can regulate gene expression, …
Cell | 空间多组学揭示TCF4依赖性基因调控网络赋予黑色素瘤对免 …
tcf4是mes特征的核心调控因子，也是黑色素细胞和抗原递呈转录程序的抑制因子，是这一特征的枢纽，使用溴域抑制剂在基因上或药理学上靶向tcf4可增加mes细胞的免疫原性和对icb及靶向 …
A TCF4-dependent gene regulatory network confers resistance to ...
Jan 4, 2024 · Targeting TCF4 genetically or pharmacologically, using a bromodomain inhibitor, increased immunogenicity and sensitivity of MES cells to ICB and targeted therapy. We …
Transcription factor 4 and its association with psychiatric disorders
Jan 5, 2021 · The human transcription factor 4 gene (TCF4) encodes a helix–loop–helix transcription factor widely expressed throughout the body and during neural development.
Transcription factor TCF4: structure, function, and associated
This review focuses on the TCF4 gene that encodes a transcription factor crucial for nervous system development and functioning. Pathogenic variants in this gene have been linked to a …
TCF4 transcription factor 4 [ Homo sapiens (human) ]
Feb 8, 2025 · TCF4 is a widely used alternative name for T-cell-specific transcription factor 4 (TCF7L2) conflicting with the official symbol for transcription factor 4 (TCF4). [08 Feb 2019] …
转录因子 4（TCF4）基因 | MCE - MCE-生物活性分子大师
编码的蛋白质识别 Ephrussi 盒 ('E-box') 结合位点 ('CANNTG') - 一个在免疫球蛋白增强剂中首次发现的基序。 该基因广泛表达，可能在神经系统发育中发挥重要作用。 该基因的缺陷是皮特-霍 …