TACC3 Gene - GeneCards | TACC3 Protein | TACC3 Antibody
2025年3月30日 · TACC3 (Transforming Acidic Coiled-Coil Containing Protein 3) is a Protein Coding gene. Diseases associated with TACC3 include Gliosarcoma and Giant Cell …
TACC3: a multi-functional protein promoting cancer cell survival …
2025年1月24日 · Multiple ways of regulation of TACC3 expression in cancer cells. E2F1 transcribes TACC3, and TACC3 is in a feed-forward loop with E2F1 via promoting its activity …
Targeting TACC3 represents a novel vulnerability in highly …
2023年3月2日 · A TACC3 mRNA expression in breast cancer tumors in the METABRIC dataset with low vs. high CA20 score.B Survival analyses in breast cancer patients based on CA20 …
A Highly Potent TACC3 Inhibitor as a Novel Anticancer Drug ... - PubMed
TACC3, a transforming acidic coiled-coil (TACC) family member, is frequently upregulated in a broad spectrum of cancers, including breast cancer. It plays critical roles in protecting …
含转化酸性卷曲螺旋 3（TACC3）基因 | MCE - MCE-生物活性 ...
含转化酸性卷曲螺旋 3： 该基因编码转化酸性大肠杆菌蛋白家族的成员。编码的蛋白质是一种运动纺锤体蛋白，可能在有丝分裂纺锤体的稳定中发挥作用。这种蛋白质也可能在某些癌细胞的生 …
Knockdown of TACC3 inhibits tumor cell proliferation and …
2023年11月27日 · Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant digestive tract tumor with limited clinical treatments. Transforming acidic coiled-coil-containing protein 3 …
TACC3: a multi-functional protein promoting cancer cell ... - PubMed
2024年1月10日 · TACC3 is the most oncogenic member of the transforming acidic coiled-coil domain-containing protein (TACC) family. It is one of the major recruitment factors of distinct …
靶向 TACC3 代表了具有中心体扩增的高度侵袭性 ... - X-MOL
我们第一次展示了，tacc3 形成不同的功能性相互作用体，调节有丝分裂和间期的不同过程，以确保 ca 癌细胞的增殖和存活。 有丝分裂 TACC3 与驱动蛋白家族成员 C1 (KIFC1) 相互作用， …
TACC3 deregulates the DNA damage response and confers
2014年4月28日 · Elevated levels of TACC3 disrupt the normal cellular response to IR. DNA damage triggers the DDR pathways in cells to recruit multiple DNA damage signaling proteins …
TACC3基因在肝癌中的表达及其与患者的预后关系
有研究表明, tacc3基因在乳腺癌, 非小细胞肺癌, 胃癌中高表达, 并与预后较差有关. 目前关于tacc3基因在肝癌中的表达情况及其与患者预后的关系鲜见报道. 本研究旨在通过生物信息学探 …