Immunohistochemical evidence for adult human neurogenesis …
2021年4月1日 · This review focuses on the findings of human post-mortem IHC in the SVZ and SGZ (Tables 1 and 2). Through a comparison of experimental methods, materials, strategies, …
High-resolution mouse subventricular zone stem-cell niche ... - PNAS
2020年11月23日 · Lineage tracing and genomic approaches have portrayed complex underlying heterogeneity within the major anatomical location for NSC, the subventricular zone (SVZ). To …
Aging of the subventricular zone neural stem cell niche: evidence …
2011年1月26日 · In the aging hippocampus, adult neural stem cells (aNSCs) shift into a quiescent state, contributing to age-related reductions in hippocampal neurogenesis. Here, we focused …
Distinct Requirements for Extracellular and Intracellular MMP12 in …
Here, we examined matrix metalloproteinases (MMPs) for potential roles in V-SVZ stem cell niche development. MMP12 was found to promote appropriate niche cellular arrangements, the …
Identification of distinct ChAT - Nature
2014年6月1日 · We identified a previously unknown population of choline acetyltransferase (ChAT) + neurons residing in the rodent SVZ neurogenic niche. These neurons showed …
The human subventricular zone: A source of new cells and a …
2007年6月1日 · In this review, we discuss and analyze the structure, cytoarchitecture and cellular composition of the human SVZ and provide a comparison to the well-studied rodent SVZ. In …
Ank3-Dependent SVZ Niche Assembly Is Required for the …
2011年7月14日 · Immunohistochemical (IHC) staining with Ank2- and Ank3-specific antibodies on P14 brain lateral ventricular whole mounts demonstrated that while Ank2 was ubiquitously …
科研│PNAS：高分辨率小鼠脑室下区干细胞微环境转录组揭示了谱 …
2021年4月20日 · CGD小鼠矢状面和冠状面成年脑切片的免疫组织化学（IHC）染色证实Glast、CD133和GFAP抗体修饰了最密集的GFP+核（图1E和F），SVZ组织的整体染色显示GFP+ / …
Post-injury protective astrogenesis from SVZ niche is controlled by ...
2013年5月5日 · We induced cortical injuries at P12 and examined the SVZ responses at 3 and 14 days post injury (dpi), using 3,3′-Diaminobenzidine (DAB) IHC staining against tdTomato, …
Shades of gray: The delineation of marker expression within the …
2013年12月1日 · Multiple markers must be used in combination to properly identity SVZ cell types. The research field of adult neurogenesis is rapidly expanding with more and more …