SMG9 Gene - GeneCards | SMG9 Protein | SMG9 Antibody
2024年12月25日 · SMG9 (SMG9 Nonsense Mediated MRNA Decay Factor) is a Protein Coding gene. Diseases associated with SMG9 include Heart And Brain Malformation Syndrome and …
Effect of nonsense-mediated mRNA decay factor SMG9 deficiency …
2024年5月28日 · SMG9 is an essential component of the nonsense-mediated mRNA decay (NMD) machinery, a quality control mechanism that selectively degrades aberrant transcripts. …
SMG9剪接异构体的鉴定及其功能的初步研究-学位-万方数据知识 …
SMG9（nonsensemediatedmRNAdecayfactor）是NMD通路中的重要因子，能够与SMG1形成复合体调控UPF1的磷酸化。 我们在研究过程中发现，SMG9发生了选择性剪接且产生了一种新 …
A novel variant in SMG9 causes intellectual disability, confirming a ...
2022年1月28日 · Biallelic loss-of-function variants in the SMG9 gene, encoding a regulatory subunit of the mRNA nonsense-mediated decay (NMD) machinery, are reported to cause …
SMG9 无义介导的 mRNA 衰减因子（SMG9）基因 | MCE
smg9 无义介导的 mrna 衰减因子： 该基因编码 smg1 复合物的一个调节亚基，它在无义介导的 mrna 衰变 (nmd) 中起着关键作用。 编码蛋白与 SMG1 复合激酶支架蛋白的结合导致其激酶活 …
SMG9 SMG9 nonsense mediated mRNA decay factor
2024年11月2日 · A novel variant in SMG9 causes intellectual disability, confirming a role for nonsense-mediated decay components in neurocognitive development.
SMG9 SMG9 nonsense mediated mRNA decay factor [ (human)]
Identification of a novel compound heterozygous SMG9 variants in a Chinese family with heart and brain malformation syndrome using whole exome sequencing. A novel variant in SMG9 …
Cryo-EM structure of SMG1–SMG8–SMG9 complex - Cell Research
2019年11月15日 · Here, we determined the cryo-EM structures of human SMG1 at 3.6 Å resolution and the SMG1–SMG8–SMG9 complex at 3.4 Å resolution, respectively. SMG8 has …
Entry - *613176 - SMG9 NONSENSE-MEDIATED mRNA DECAY FACTOR; SMG9 …
2024年2月12日 · HGNC Approved Gene Symbol: SMG9. Cytogenetic location: 19q13.31 Genomic coordinates (GRCh38) : 19:43,727,983-43,754,962 (from NCBI) The SMG9 gene …
SMG9 drives ferroptosis by directly inhibiting GPX4 degradation
2021年8月27日 · SMG9 positively regulates ferroptosis independent of its activity in NMD. Instead, SMG9 is a direct binding protein of GPX4 to promote the degradation of GPX4 in …