SLC15A3 Gene - GeneCards | S15A3 Protein | S15A3 Antibody
2025年3月30日 · SLC15A3 (Solute Carrier Family 15 Member 3) is a Protein Coding gene. Diseases associated with SLC15A3 include Hypotrichosis 4. Among its related pathways is …
SLC15A3 plays a crucial role in pulmonary fibrosis by regulating ...
2024年2月19日 · In this study, we demonstrated that during bleomycin (BLM)- or radiation-induced pulmonary fibrosis, the recruitment of macrophages induced an increase of SLC15A3 …
Regulation and biological role of the peptide/histidine transporter ...
2018年7月10日 · In this study, mouse peritoneal macrophages (PMs), mouse bone marrow-derived macrophages (BMDMs), the human acute monocytic leukemia cell line THP-1 and the …
溶质载体家族 15 成员 3（SLC15A3）基因 | MCE
This gene has 14 transcripts (splice variants), 121 orthologues and 4 paralogues. Broad expression in spleen (RPKM 20.2), lung (RPKM 17.9) and 23 other tissues. 启用二肽跨膜转运 …
Zhang et al. report the cryo-EM structures of the endolysosomal peptide transporters SLC15A3 and SLC15A4 in various states. The SLC15A4 structures reveal the recognition mechanisms …
SLC15A3 plays a crucial role in pulmonary fibrosis by regulating ...
The oligopeptide histidine transporter SLC15A3, mainly expressed on the lysosomal membrane of macrophages and highly expressed in the lung, has proved to be involved in innate immune …
The structures of the peptide transporters SLC15A3 and SLC15A4 …
2025年2月6日 · In this study, we aimed to determine the structures of SLC15A3 and SLC15A4 using cryo-EM techniques, the latter of which revealed the detailed structural mechanism for …
SLC15A3 deficiency enhanced macrophage antioxidant stress response, which is dependent on the regulation of the p62-NRF2 axis, thus balancing the lung...
Regulation and biological role of the peptide/histidine transporter ...
2018年7月10日 · The peptide/histidine transporter SLC15A3 is responsible for transporting histidine, certain dipeptide and peptidomimetics from inside the lysosome to cytosol. Previous …
<br>SLC15A3通过调节巨噬细胞氧化应激在肺纤维化 ... - X-MOL
寡肽组氨酸转运蛋白SLC15A3主要表达于巨噬细胞的溶酶体膜上，并在肺中高表达，已被证明参与先天免疫和抗病毒信号通路。 在这项研究中，我们证明，在博来霉素（BLM）或放射诱导的 …