Sirtuin 7 - Wikipedia
NAD-dependent deacetylase sirtuin 7 is an enzyme that in humans is encoded by the SIRT7 gene. [5][6][7] SIRT7 is member of the mammalian sirtuin family of proteins, which are …
去乙酰化转移酶SIRT7的作用及机制研究进展
As a member of the Sirtuins family in mammals, SIRT7 locates in nucleus and is a highly specific H3K18Ac (acetylated lysine 18 of histone H3) deacetylase. Recent studies showed that SIRT7 …
SIRT7 Gene - GeneCards | SIR7 Protein | SIR7 Antibody
2025年3月30日 · SIRT7 (Sirtuin 7) is a Protein Coding gene. Diseases associated with SIRT7 include Prostate Cancer and Lysosomal Storage Disease. Among its related pathways are …
Structural basis of SIRT7 nucleosome engagement and substrate …
2025年2月4日 · Here, we report structures of nucleosome-bound SIRT7, and uncover the structural basis of its specificity towards H3K36 and K18 deacylation, combining a mechanism …
长寿蛋白Sirtuins家族SIRT1到SIRT7，分别参与哪些生理过程？ - 知乎
sirt7能够支持心脏细胞功能，保护心肌细胞免受氧化应激和炎症损伤，延缓心脏因年龄增长而出现的退化。此外，sirt7还与dna修复相关，可以延长心脏细胞的寿命，帮助维持心血管系统的稳 …
SIRT7 is a histone desuccinylase that functionally links to …
2016年7月20日 · We show that SIRT7 is recruited to DNA double-strand breaks (DSBs) in a PARP1-dependent manner and catalyses desuccinylation of H3K122 therein, thereby …
SIRT7基因的功能与作用机制解析 - 八方基因
2025年1月8日 · 本文将详细介绍SIRT7基因的功能、作用机制、涉及的信号通路以及与疾病的关系，帮助读者全面了解这一重要的基因。 SIRT7基因概述 SIRT7，全称sirtuin 7，是Sirtuins家族 …
SIRT7 regulates T-cell antitumor immunity through modulation
2025年3月26日 · SIRT7, one of the least studied members of the Sirtuins family, is an NAD+-dependent lysine deacetylase and desuccinylase. While previous studies using affinity …
The seven faces of SIRT7 - PMC
SIRT7, a member of the sirtuin family of NAD +-dependent protein deacetylases, is a key mediator of many cellular activities. SIRT7 expression is linked to cell proliferation and …
余红秀团队揭示SIRT7通过调控BCAA和脂肪酸代谢增强T细胞抗肿 …
2025 年 3 月 26 日，复旦大学生物医学研究院、附属口腔医院 余红秀 教授团队在 Cell Death & Differentiation 杂志发表了题为" SIRT7 regulates T-cell antitumor immunity through modulation …
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