A seizure (from the Latin sacire—to take possession of) is the clinical manifestation of an abnormal, excessive, hypersynchronous discharge of a population of cortical neurons. …

2022年4月2日 · The International League Against Epilepsy (ILAE) proposed a new classification framework in 2017 which included six etiologic categories of seizures and epilepsies. This …

2023年2月7日 · Generalized seizures result from diffuse cortical activation at seizure onset or generalization of partial seizure activity. This activity discusses the evaluation and …

2023年7月10日 · Identify the various classes of anti-seizure medications and their mechanisms of action. Review the indications for therapy initiation by seizure drug subclass. Describe the …

Decades of experimental work have established an imbalance of excitation and inhibition as the leading mechanism of the transition from normal brain function to seizure. In epilepsy, these …

Hyperactivity of excitatory amino acid systems, insufficient GABAA receptor-mediated neurotransmission, and disturbances in intrinsic properties of neuronal membranes are still …

Spread of seizure discharges beyond the hippocampus is common. Seizures often become intractable and affective comorbidities are frequent. When two medications fail, a surgical …

Acute and severe electrolyte imbalances can manifest with seizures, which may be the sole presenting symptom. Seizures are more frequently observed in patients with sodium disorders …

A febrile seizure is a neurological abnormality that occurs as a result of a peripheral infection, to which the immune system reacts by producing an inflammatory response thereby, inducing a …

Mechanisms of MgSO 4 for seizure prevention MgSO 4 is the therapy of choice for preventing eclamptic convulsions. The mechanisms by which MgSO 4 is effective at preventing eclamptic …