Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial (CybS), also known as succinate dehydrogenase complex subunit D (SDHD), is a protein that in humans is …

May 21, 2008 · The diagnosis is established in a proband with a personal or family history of paraganglioma or pheochromocytoma and a germline heterozygous pathogenic variant in …

The SDHD gene provides instructions for making one of four subunits of the succinate dehydrogenase (SDH) enzyme. The SDH enzyme plays a critical role in mitochondria, which …

Mar 30, 2025 · SDHD (Succinate Dehydrogenase Complex Subunit D) is a Protein Coding gene. Diseases associated with SDHD include Pheochromocytoma/Paraganglioma Syndrome 1 and …

Hereditary paraganglioma-pheochromocytoma is an inherited condition characterized by the growth of tumors in structures called paraganglia. Paraganglia are groups of cells that are …

Dec 12, 2024 · If you have a mutation in the SDHD gene, this means you have a condition called hereditary paraganglioma-pheochromocytoma (PGL/PCC) syndrome. SDHD mutations …

Jun 12, 2021 · Succinate dehydrogenase (Complex II) plays a dual role in respiration by catalyzing the oxidation of succinate to fumarate in the mitochondrial Krebs cycle and …

Carriers of succinate dehydrogenase (SDHx) mutations are at risk of developing phaeochromocytomas, catecholamine secreting extra-adrenal paragangliomas and non …

Aug 27, 2024 · Complex II subunit SDHD is critical for cell growth and metabolism, which can be partially restored with a synthetic ubiquinone analog. Bandara AB, Drake JC, Brown …

SDHD, an enzyme complex consisting of four subunits A, B, C and D, catalyzes the oxidation of succinate to fumarate with the reduction of ubiquinone to ubiquinol. From: Biochimica et …