2023年5月23日 · Identify the mechanism of action of scopolamine. Describe the potential adverse effects of scopolamine. Explain the signs of scopolamine toxicity and its proper management.

Scopolamine is a belladonna alkaloid with anticholinergic effects indicated for the treatment of nausea and vomiting associated with motion sickness and postoperative nausea and vomiting (PONV).

2024年9月10日 · This activity discusses scopolamine, an antimuscarinic agent for managing motion sickness and postoperative nausea and vomiting. By focusing on scopolamine's mechanism of action, indications, and contraindications, healthcare professionals gain essential insights for efficacious patient care.

Scopolamine, also known as hyoscine, [9] or Devil's Breath, [10] is a natural or synthetically produced tropane alkaloid and anticholinergic drug that is used as a medication to treat motion sickness [11] and postoperative nausea and vomiting.

2020年2月10日 · Blocks the action of acetylcholine at parasympathetic sites in smooth muscle, secretory glands and the CNS; increases cardiac output, dries secretions, antagonizes histamine and serotonin; at usual recommended doses, causes blockade of muscarinic receptors at the cardiac SA-node and is parasympatholytic (ie, blocks vagal activity increasing hear...

2022年9月26日 · Scopolamine is the most commonly encountered medication in this class. It works by antagonizing the M1 muscarinic receptor. It is predominantly used to treat motion sickness or prophylactically in the perioperative setting.

2020年8月14日 · Butylscopolamine is a peripherally acting antimuscarinic, anticholinergic agent. It is used to treat pain and discomfort caused by abdominal cramps, menstrual cramps, or other spasmodic activity in the digestive system. It is also effective at preventing bladder spasms.

2023年5月23日 · Scopolamine is a medication used to manage and treat postoperative nausea and vomiting (PONV) and motion sickness. It is in the anticholinergic class of drugs. This activity will highlight the indications, mechanism of action, adverse event profile, and other key factors (e.g., off-label uses, dosin …

Scopolamine acts as a non-selective competitive inhibitor of M1-M5 mAChRs, albeit with weaker M5 inhibition; as such, scopolamine is an anticholinergic with various dose-dependent therapeutic and adverse effects.

The prevention and control of motion sickness symptoms has involved the use of pharmacological interventions, behavioural therapy and complementary medicine with varying success. Scopolamine (hyoscine), an anticholinergic, is one of the most commonly used pharmacological agents for motion sickness.