2024年9月6日 · Exposure to large doses of sarin by any type of exposure would likely cause the following harmful health effects: If sarin is in the air, people can be exposed through skin or eye contact, or breathing in the sarin gas. Because sarin vapor is heavier than air, it will sink to low-lying areas and increase the risk of exposure there.

Long-term effects after exposure to OP nerve agents. Years after exposure to sarin, victims of the Tokyo subway attack presented with significant declines in psychomotor and memory functions, 46,47 signifying long-term cognitive impairment.

2024年11月21日 · We know that exposure to sarin can result in death, or short-term health effects including seizures, paralysis, and difficulty breathing within 24 hours of exposure. In contrast, long-term health effects of sarin exposure could be observed days, weeks, or …

Initial symptoms following exposure to sarin are a runny nose, tightness in the chest, and constriction of the pupils (miotic action). Soon after, the person will have difficulty breathing and experience nausea and drooling. This progresses to losing control of bodily functions, which may cause the person to vomit, defecate, and urinate.

Exposure to high doses of sarin can result in tremors, seizures, and hypothermia. A more severe effect of sarin is the build-up of ACh in the central nervous system (CNS) which causes paralysis and ultimately peripherally-mediated respiratory arrest, leading to death.

Sarin (military designation GB) is a nerve agent that is one of the most toxic of the known chemical warfare agents. It is generally odorless and tasteless. Exposure to sarin can cause death in minutes.

2002年10月1日 · Toxicity from sarin significantly increased following concurrent exposure to other chemicals such as pyridostigmine bromide. Further research to examine effects of sarin on the cellular and the molecular levels, gene transcription, endocrine system as well as its long-term impact is needed.

Immediate effects of acute sarin exposure are established; however, whether effects persist after initial signs have subsided is debated. The National Toxicology Program (NTP) con-ducted a systematic review to evaluate the evidence for long-term neurological effects following acute (<24 hour) exposure to sarin.

2019年1月21日 · There is a consistent pattern of findings that pupil constriction from acute sarin exposure gradually normalizes in the following week to several months. There is a moderate level of evidence from human studies that sarin has negative effects on vision in the intermediate time period including decreases in visual evoked potentials.

Sarin is a nerve agent developed for chemical warfare during World War II. This highly toxic nerve agent (which can cause death, seizures, and immediate cholinergic symptoms) is liquid at ambient temperatures. It is also known as GB, which is a two-character identifier assigned by the North Atlantic Treaty Organization (NATO).