肥厚型心肌病是一种以左心室壁不对称性肥厚为解剖特征的遗传性心脏病，通过2D超声心动图或心血管磁共振在最大舒张末期发现任意一个左心室室壁节段厚度≥ 15 mm，且肥厚不能由其他原因所解释即可临床诊断 [1-2]。 它影响着0.2%以上的成年人群，是临床上导致青少年和运动员心源性猝死的最常见疾病之一 [3]。 若存在 左心室流出道梗阻 （left ventricular outflow tract obstruction, LVOTO），即称为肥厚型梗阻性心肌病（hypertrophic obstructive cardiomyopathy, HOCM）。

2024年2月22日 · SAM is a common cause of subaortic stenosis that can lead to LVOTO, LV hypertrophy, increase in end diastolic pressure, oxygen demand and supply mismatch, and functional mitral regurgitation (MR). Treatment is achieved by excision of the membrane, mobilization of the trigons, and extended septal myectomy.

2019年12月19日 · Subaortic membrane resection is a surgery that’s used to repair a medical condition known as subaortic stenosis. With subaortic stenosis, the area just below the aortic valve of the left ventricle is obstructed or narrowed often by excess tissue, which reduces the flow of blood to the body.

2001年1月1日 · Transaortic resection of SAM was done in all patients along with excision of a wedge-shaped segment of septal muscle underlying the membrane. Results: There were no early or late postoperative deaths. On follow up (up to 113 months), only four patients had gradients >30 mmHg. LVEF improved to 45–70% (mean 58 ± 7.7%).

Transaortic resection of SAM was done in all patients along with excision of a wedge-shaped segment of septal muscle underlying the membrane. Results: There were no early or late postoperative deaths. On follow up (up to 113 months), only four patients had gradients >30 mmHg. LVEF improved to 45-70% (mean 58 +/- 7.7%).

This explains why obstructive SAM can accompany modest septal hypertrophy when excessive or segmental leaflet elongation and papillary muscle malposition is present. This mechanism is important to understand and to be addressed to prevent the persistentance of …

Subaortic stenosis is the second most common form of left ventricular outflow tract (LVOT) obstruction after valvular aortic stenosis. We are reporting the largest case series of SAM and PDA. We included all patients that were diagnosed with the combination of …

2023年11月9日 · The discussion highlights the challenges in diagnosing SAM, the importance of imaging studies, and the potential complications associated with SAM in young patients. The article also explores the management options for SAM, emphasizing surgical resection as the definitive treatment, while acknowledging the limited success rates of alternative ...

2001年1月1日 · Transaortic resection of SAM was done in all patients along with excision of a wedge-shaped segment of septal muscle underlying the membrane. Results: There were no early or late postoperative deaths. On follow up (up to 113 months), only four patients had gradients >30 mmHg. LVEF improved to 45–70% (mean 58 ± 7.7%).

Transaortic SAM resection is an acceptable treatment, but it is associated with a high incidence of recurrence requiring reoperation (6%-30%). Therefore, it is reasonable to consider alternative therapies, such as septal myomectomy, which is associated with a lower rate of recurrence (up to 4%), particularly in cardiac reinterventions.