2025年3月30日 · SAG (S-Antigen Visual Arrestin) is a Protein Coding gene. Diseases associated with SAG include Retinitis Pigmentosa 47 and Oguchi Disease 1. Among its related pathways …

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular …

6 天之前 · Title: A Novel Dominant Mutation in SAG, the Arrestin-1 Gene, Is a Common Cause of Retinitis Pigmentosa in Hispanic Families in the Southwestern United States. Macular …

2023年1月30日 · A novel dominant mutation in SAG, the arrestin-1 gene, is a common cause of retinitis pigmentosa in Hispanic families in the southwestern United States. Invest.

Arrestin /beta-arrestin 蛋白家族的成员被认为参与激动剂介导的 G 蛋白偶联受体脱敏，并导致细胞对激素、神经递质或感觉信号等刺激的反应发生特异性抑制。 S-arrestin，也称为 S-抗原，是 …

We describe a case of Oguchi disease with unusual findings caused by a putative heterozygous mutation in the SAG gene. maintenance of low levels of the active monomer is the biological …

Oguchi type 1 disease is an autosomal recessive condition caused by mutations in the arrestin ( SAG) gene (2q37.1) whose product is an intrinsic photoreceptor protein that participates in the …

SAG的详细信息，包括基因名称，代码，染色体位置，相互作用关系和通路，简述为休止/β-类休止蛋白家族的成员被认为参与G蛋白偶联受体的激动剂介导的脱敏而导致的细胞应答特异性衰减 …

2018年6月26日 · SAG, also known as S-antigen or S-arrestin, encodes a rod photoreceptor protein involved in the recovery phase of light transduction. It is present in the retina and …

Our data show that SAG expression is threefold higher in senescent fibroblasts and closely parallels the progressive slowdown in growth potential, but is not cell-cycle regulated. Thus, …