A nuclear matrix-associated factor, SAF-B, interacts with ... - PubMed
2000年8月15日 · Using this domain as a probe, we performed a yeast two-hybrid screening and we found that scaffold attachment factor B (SAF-B), a nuclear matrix-associated protein, …
Nature顶刊详解｜Direct RNA测序助力解析基因组守护者SAFB蛋白 …
2024年3月21日 · 免疫印迹结果显示，L1转染细胞中单独敲除SAFB或L1转录调节因子HUSH，会导致ORF1p表达水平相同程度的增加，并且同时敲除时，表达水平增加会更加明显（图2g）， …
支架附着因子 B（SAFB）基因 | MCE - MCE-生物活性分子大师
该基因编码一种 DNA 结合蛋白，该蛋白对支架或基质附着区域 DNA 元件 (S/MAR DNA) 具有高度特异性。 这种蛋白质被认为与将染色质环的碱基连接到核基质有关，但关于这种蛋白质是染 …
The Nuclear Matrix Protein SAFB Cooperates with Major Satellite …
2020年1月16日 · Here, we show that scaffold attachment factor B (SAFB), a nuclear matrix (NM)-associated protein with RNA-binding functions, modulates chromatin condensation and …
SAFB Gene - GeneCards | SAFB1 Protein | SAFB1 Antibody
2025年3月30日 · SAFB (Scaffold Attachment Factor B) is a Protein Coding gene. Diseases associated with SAFB include Denys-Drash Syndrome and Fanconi Anemia, …
SAFB restricts contact domain boundaries associated with L1 …
2024年4月10日 · SAFB depletion increases the RNA Pol II enrichment, elevates L1 chimeric RNAs, and strengthens the domain boundaries. Heatmaps show the aggregated Hi-C contact …
The Nuclear Matrix Protein SAFB Cooperates with Major ... - PubMed
2020年1月16日 · Here, we show that scaffold attachment factor B (SAFB), a nuclear matrix (NM)-associated protein with RNA-binding functions, modulates chromatin condensation and …
Scaffold attachment factor B: distribution and interaction
Co-immunoprecipitation experiments revealed that both SAFB proteins from the MPOA reciprocally interact with endogenous ERα. These results indicate that, in addition to a role in …
A novel hnRNP protein (HAP/SAF-B) enters a subset of hnRNP …
1999年5月15日 · HAP was found to be identical to the previously described Scaffold Attachment Factor B (SAF-B) and to HET, a transcriptional regulator of the Heat Shock Protein 27 gene. …
生命学院刘念团队揭示L1反转录转座子的转录活性调控染色质拓扑 …
2024年4月18日 · 同时，核基质蛋白Scaffold Attachment Factor B（SAFB）对L1这一功能具有抑制作用。SAFB通过识别L1 RNA转录本来结合转录活跃的L1 DNA，抑制Pol II在L1上的聚集， …