The serum ascites albumin gradient (SAAG) is a formula used to assist in determining the etiology of ascites. Also see Medscape’s Ascites Albumin Gradient Calculator. The formula is...

The Serum Ascites Albumin Gradient (SAAG) defines presence of portal hypertension (does not differentiate cause) in patients with ascites.

Ascitic fluid analyses indicating gross appearance, biochemical tests (e.g. SAAG, LDH, glucose, amylase, and ADA), and non-biochemical tests (e.g. cell counts, bacterial culture and PCR, viscosity, 1 H NMR spectroscopy, VEGF, and tumor markers) can provide useful clues in the differential diagnosis of ascites and help in establishing a ...

2025年2月14日 · The serum–ascites albumin gradient (SAAG) is the difference between the concurrently obtained serum albumin concentration and the albumin concentration of the ascitic fluid obtained during paracentesis.

The most important parameter to determine the cause of ascites is the serum‐ascites albumin gradient (SAAG). The SAAG correlates with the sinusoidal pressure,6 and a SAAG ≥1.1 g/dL (high SAAG ascites) indicates a hepatic vein–portal vein pressure gradient more than 11 mm Hg (i.e., portal hypertension). High SAAG ascites is almost always ...

Underlying etiologies of ascites with a high SAAG (≥11 g/L) or a low SAAG (<11 g/L) are described in Tables 2 and 5. Therefore, SAAG has been recognized as a reliable marker in the differentiation of portal hypertension from non-portal hypertension, and recommended as an initial ascitic fluid analysis according to clinical practice guidelines ...

2023年12月20日 · Routine ascitic fluid analysis should include the serum ascites albumin gradient (SAAG), total protein concentration, cell count and differential. Optional ascitic fluid analysis includes cholesterol, fluid culture, cytology, tumor markers, lactate dehydrogenase, adenosine deaminase (ADA), triglyceride, amylase, glucose, brain natriuretic ...

Ascites is broadly classified as two types based on the serum-ascites albumin gradient (SAAG): Transudate - SAAG > 1.1 g/dL (indicative of ascites due to portal hypertension ) Exudate - SAAG < 1.1 g/dL (indicative of ascites due to other etiologies )

The difference between the albumin concentration between serum and AF, called serum-ascites albumin gradient (SAAG), reflects directly and indirectly the colloid osmotic pressure and the degree of portal hypertension . Pare et al suggested that SAAG is a better discriminator of portal hypertension than protein concentration in AF.

The serum-ascites albumin gradient (SAAG) helps determine the cause of ascites. SAAG = albumin concentration of serum - albumin concentration of ascitic fluid. The SAAG is probably a better discriminant than older measures (transudate versus exudate) for the causes of ascites. [1] .