Suppression of tumorigenicity 5 is a protein that in humans is encoded by the ST5 gene. [5] [6] ST5 orthologs [7] have been identified in nearly all mammals for which complete genome data are available.

2025年3月28日 · DENND2B (DENN Domain Containing 2B) is a Protein Coding gene. Diseases associated with DENND2B include Meningococcal Meningitis and Oral Candidiasis. Among its related pathways are Vesicle-mediated transport and Rab regulation of trafficking. An important paralog of this gene is DENND2A.

2010年6月4日 · They mapped the mouse St5 gene to distal chromosome 7 in a region that shows homology of synteny to human chromosome 11p15.3. In both genomes, ST5 lies telomeric to the CEGF1 gene and centromeric to the LMO1 gene ( 186921 ).

ST5 - Explore an overview of ST5, with a histogram displaying coding mutations, full tabulated details of all associated variants, tissue distribution and any drug resistance data.

探讨肿瘤抑制基因5(st5)在低分化胃腺癌发生中的作用。 方法 应用甲基化芯片技术来建立人低分化胃腺癌甲基化谱，分析ST5基因在人低分化胃癌组织中甲基化。

ST5, HTS1, p126. Location: 11p15.4. Summary: This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins.

A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt.

1999年4月15日 · We now report the detection of ST5 proteins in cellular extracts, demonstrate specific expression of p70 in non-tumorigenic HeLa-fibroblast hybrids, extend the correlation between p70 expression...

Our findings suggest that ST5 potentially acts as a tumor suppressor gene in invasive breast cancer through regulating ERK/JNK signaling pathway and provide a novel insight for breast cancer treatment. Keywords: suppression of tumorigenicity …

2021年7月28日 · Our findings suggest that ST5 potentially acts as a tumor suppressor gene in invasive breast cancer through regulating ERK/JNK signaling pathway and provide a novel insight for breast cancer treatment.