ST2 and the ST2/IL-33 signalling pathway–biochemistry and ...
2019年8月1日 · IL-33 is the functional ligand of ST2L and signals the presence of tissue damage to local immune cells. IL-33/ST2L signalling leads to the production of inflammatory …
ST2 and the ST2/IL-33 signalling pathway-biochemistry and
IL-33 is the functional ligand of ST2L and signals the presence of tissue damage to local immune cells. IL-33/ST2L signalling leads to the production of inflammatory cytokines/chemokines and …
Pro- and anti-inflammatory roles of interleukin (IL)-33, IL-36, and …
2022年11月14日 · All IL-36 cytokines bind to the IL-36R complex and exert various functions through NF-κB and mitogen-activated protein kinase (MAPK) pathways in inflammatory …
白细胞介素-36 (IL-36) - 丁香通
2017年9月12日 · il-36 受体拮抗剂 (il-36ra) 分布于皮肤、心脏、肾脏和大脑中，可由单核细胞、b 淋巴细胞树突状细胞等细胞产生，能够与 il-36r 结合，也有研究者把 il-36ra 归为 il-36 家族， …
IL-36 family cytokines in protective versus destructive inflammation
2020年11月1日 · Here we summarize signaling pathways regulated by IL-36 family cytokines, including IL-38, and the consequences for physiological protective and pathophysiological …
Frontiers | Biology of IL-36 Signaling and Its Role in Systemic ...
Interleukin (IL)-36 signal pathways induce inflammatory responses. Pro-IL-36 cytokines are inactive proteins and require post-translational processing to fully unleash the pro …
Combined inhibition of IL-1, IL-33 and IL-36 signalling by …
IL1RAP is an essential coreceptor for the IL1R, the IL33R (ST2) and the IL36R and is required for the activation of intracellular downstream targets by these cytokines. 16 CAN10 is a …
可溶性生长刺激表达基因2蛋白在冠心病与心力衰竭的临床应用及 …
IL-33/ST2L通路具有抗动脉粥样硬化、抗心肌肥厚、抗心肌纤维化等多种心血管保护作用，而sST2作为一种诱骗受体，与IL-33结合则可以阻断上述生物学作用。 近来研究发现，sST2作 …
ST2/IL-33信号通路-生长刺激表达基因2蛋白（ST2）临床意义-欧凯 …
ST2有两种主要的亚型：①跨膜型ST2（ST2L），具有跨膜结构，含有跨膜片段和Toll/IL-1TR受体胞内结构域；②可溶型ST2（sST2），无跨膜结构，可分泌到细胞外。2005年Schmitz等研究 …
IL-36 Cytokines: Regulators of Inflammatory Responses and Their ...
MDDCs stimulated with IL-36α enhance allogeneic CD4+ T cell proliferation. IL-36 may influence T cell function in skin via its effects on APCs and their expression of Th17-inducing IL-1β and …