Sterol regulatory element-binding protein 1 - Wikipedia
Sterol regulatory element-binding transcription factor 1 (SREBF1) also known as sterol regulatory element-binding protein 1 (SREBP-1) is a protein that in humans is encoded by the SREBF1 …
SREBP_百度百科
Sterol-regulatory element binding proteins (SREBPs)胆固醇调节元件结合蛋白 (SREBP)是位于内质网的细胞内胆固醇敏感器，通过Insig-Srebp-Scap途径对细胞内胆固醇进行反馈调节。
Sterol regulatory element-binding protein 1（SREBP1）
SREBP1（固醇调节元件结合蛋白1）是调控脂合成的重要转录调控因子，其合成后以非活性前体的形式存在于内质网。 当固醇浓度低时，SREBP1以依赖于COPII的方式从内质网转运到高尔 …
SREBF1 Gene - GeneCards | SRBP1 Protein | SRBP1 Antibody
2025年3月30日 · SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1) is a Protein Coding gene. Diseases associated with SREBF1 include Ifap Syndrome 2 and Mucoepithelial …
In this review, we summarize the feature of target genes regulated by SREBP-1, emphatically introduce the role of insulin and other upstream factors in regulating SREBP-1, which will …
miR-122 已被证明可以通过靶向SREBP-1 来调节脂肪酸代谢:该项研究比较了NASH患者与正常人的474 种miRNAs 的表达,通过microRNA 微阵列分析并用RT-PCR 验证,发现miR-122的表达存 …
SREBPs in Lipid Metabolism, Insulin Signaling, and Beyond
The SREBP-1 gene gives rise to SREBP-1a and SREBP-1c, which are derived from utilization of alternate promoters that yield transcripts in which distinct first exons are spliced to a common …
Sterol regulatory element-binding protein - Wikipedia
SREBP-1c is responsible for regulating the genes required for de novo lipogenesis. [6] SREBP-2 regulates the genes of cholesterol metabolism. [6] SREB proteins are indirectly required for …
Sterol regulatory element binding protein 1 couples …
2019年3月22日 · In this work, we identified acto-myosin contractility and mechanical forces imposed by the extracellular matrix (ECM) as SREBP1 regulators. SREBP1 control by …
Science | 颜宁/闫创业合作解析固醇感受器分子机制 - 知乎
2021年1月15日 · 哺乳动物中，SREBP有三种不同的形式，分别是SREBP-1a, SREBP-1c和SREBP-2。 SREBP-1系列主要负责脂肪的从头合成，a和c在不同的组织中的表达谱不一 …