2016年6月28日 · Silicon based anti-resonant reflecting optical waveguide type B (ARROW-B) SPR biosensors allow high-sensitivity detection of label-free biomolecular interactions in real time. These biosensors were fabricated by semiconductor fabrication process with …

2025年1月15日 · Surface plasmon resonance (SPR) is a powerful optical phenomenon obtained by the interaction of polarized light with the interface of the negative–positive permittivity in a metal (having negative permittivity) and a dielectric medium (having positive permittivity) [1].

2024年9月27日 · Surface plasmon resonance (SPR) biosensors have become crucial in biochemistry and biophysics due to their high sensitivity in detecting biomolecular interactions. These sensors operate by monitoring changes in the refractive index near metal surfaces, typically gold or silver.

2025年3月1日 · Integration with AI enables portable SPR biosensors to achieve a detection resolution of up to 10 −7 RIU level. AI-assisted analysis shows potential to advance SPR biosensing in biomedical and environmental fields.

2023年12月1日 · This review highlights the most recent advancements in SPR biosensor technology including strategies for increasing sensitivity and selectivity and its various configurations, including improvements in prism, grating, fiber …

2015年5月5日 · Surface plasmon resonance (SPR) is a label-free detection method which has emerged during the last two decades as a suitable and reliable platform in clinical analysis for biomolecular interactions. The technique makes it possible to measure interactions in real-time with high sensitivity and without the need of labels.

2025年3月5日 · Based on this SPR effect, the optimal conditions for various sensitive materials were explored and experimental characterization was done accordingly, and finally the proposed optical fiber biosensor was prepared. The β2-MG sensor showed a linear sensitivity of 0.96 nm/lg c and a LOD of 4.22 ng/mL in the range of 0.01-1000 ng/mL.

3 天之前 · This study demonstrates a new sulfide material-based structure for SARS-CoV-2 detection using a prism-based SPR nano-biosensor. In which case, this is a designed configuration inspired by the Kretschmann configuration, silver, zinc telluride, zinc sulfide layer, 2D materials of black phosphorus and graphene, and a sensing medium that takes ...

2025年1月9日 · SPR-based biosensors have emerged as a versatile and sensitive platform for real-time, label-free detection in various fields. Their ability to monitor biomolecular interactions with high specificity and precision has led to their adoption in diverse applications, ranging from healthcare to environmental safety and beyond.

4 天之前 · Photonic biosensors have also been developed for detecting viral antigens in respiratory samples to diagnose active SARS-CoV-2 infections. Chen et al. introduced a handheld SPR biosensor using light-emitting perovskite composites for Spike protein detection in nasopharyngeal samples, evaluated with four clinical samples against PCR and LFAs.