006361 - Osx1-GFP::Cre Strain Details - The Jackson Laboratory
These Osx1-GFP::Cre mutant mice may be useful in studies of bone development, osteoblast lineage and Hedgehog/Wnt signaling. 006361 B6.Cg-Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/J Cre …
Control of osteocyte dendrite formation by Sp7 and its target …
2021年11月1日 · Osteocrin is a Sp7 target gene that promotes osteocyte dendrite formation and rescues defects in Sp7-deficient mice. Single-cell RNA-sequencing demonstrates defects in …
Roles of Sp7 in osteoblasts for the proliferation, differentiation, …
2024年7月1日 · Our studies indicated that Sp7 inhibits the proliferation of immature osteoblasts, induces osteoblast maturation and Col1a1 expression, and is required for osteocytes to …
SP7 Inhibits Osteoblast Differentiation at a Late Stage in Mice
2012年3月2日 · Sp7 transgenic mice showed osteopenia due to the inhibition of osteoblast differentiation at a late stage, which was shown by woven bone structure in the cortical bone, …
SP7: from Bone Development to Skeletal Disease - Springer
2023年3月7日 · Chondrocyte-specific deletion of Sp7 (Col2a1-Cre; Sp7 fl/+) in mice results in impaired endochondral bone formation including delayed chondrocyte differentiation, …
Sp7 Sp7 transcription factor 7 [ (house mouse)] - National Center …
2025年2月8日 · Sp7 Transgenic Mice with a Markedly Impaired Lacunocanalicular Network Induced Sost and Reduced Bone Mass by Unloading. A neomorphic variant in SP7 alters …
Osx-Cre targets multiple cell types besides osteoblast lineage in ...
2014年1月15日 · Osterix (Osx or Sp7) is a zinc-finger-family transcriptional factor essential for osteoblast differentiation in mammals. The Osx-Cre mouse line (also known as Osx1 …
骨科Cre鼠高分助攻相关疾病研究|BioMice百奥动物
2023年10月30日 · 百奥动物发开了B-Sp7-iCre mice、B-Prrx1-iCre mice、B-Col2a1-iCre mice、B-Dmp1-iCre mice等可用于研究成骨细胞分化过程中特定细胞类型的Cre工具鼠模型。 骨科Cre鼠 …
Roles of Sp7 in osteoblasts for the proliferation ... - PubMed
2024年6月24日 · Methods: Sp7 floxneo/floxneo mice, in which Sp7 expression was 30 % of that in wild-type mice because of disturbed splicing by neo gene insertion, and osteoblast-specific …
SP7 Inhibits Osteoblast Differentiation at a Late Stage in Mice
2012年3月2日 · Sp7 transgenic mice showed osteopenia due to the inhibition of osteoblast differentiation at a late stage, which was shown by woven bone structure in the cortical bone, …