Rutin is a rutinoside that is quercetin with the hydroxy group at position C-3 substituted with glucose and rhamnose sugar groups. It has a role as a metabolite and an antioxidant. It is a disaccharide derivative, a quercetin O-glucoside, a tetrahydroxyflavone and a rutinoside.

Rutin is a citrus flavonoid glycoside found in many plants, including buckwheat, [7] the leaves and petioles of Rheum species, and asparagus. Tartary buckwheat seeds have been found to contain more rutin (about 0.8–1.7% dry weight) than common buckwheat seeds (0.01% dry weight). [7] Rutin is one of the primary flavonols found in 'clingstone' peaches. [8] It …

Rutin exerts anti-inflammatory effects in ultraviolet B-irradiated mouse skin by inhibiting the expression of cyclooxygenase-2 and inducible nitric oxide synthase (Choi et al., 2014). Rutin has only a weak and short-term anticonvulsant potential.

Rutin caused attenuation of streptozotocin-induced inflammation by decreasing the activity of the glial fibrillary acidic protein, interleukin-8, cyclooxygenase-2, inducible nitric oxide synthase and nuclear factor-kB and thereby prevented gross anatomical changes in rat hippocampus.

Rutin (vitamin P or rutoside) is a citrus flavonoid glycoside that has shown beneficial health effects in different organs against various conditions including inflammation and pain. The majority of rutin therapeutic benefits are ascribed to its antioxidant and anti-inflammatory properties.

6 天之前 · Background Emerging evidence suggests that chronic stress compromises blood‒brain barrier (BBB) integrity by disrupting brain microvascular endothelial cells (BMECs), contributing to the development of cognitive impairments. Thus, targeting the BBB is expected to be a promising treatment strategy. The biological function of rutin has …

2017年9月1日 · Rutin (3′,4′,5,7-tetrahydroxy-flavone-3-rutinoside) is a flavonol glycoside (Table 1), which has been reported to present clinically relevant functions, potentially beneficial in preventing diseases and protecting genome stability (Sharma, Ali, Ali, Sahni, & Baboota, 2013a).

2025年3月1日 · Mechanistic studies demonstrated that rutin alleviated oxidative stress by enhancing antioxidant enzyme activities and reducing lipid peroxidation, as well as suppressing inflammatory responses and downregulated indoleamine 2, 3-dioxygenase (IDO) activity/expression.

The first involves transforming rutin into nanocrystals without the use of any secondary compounds. The second approach entails nano-formulating rutin with other compounds, including proteins, polysaccharides, lipids, polymers, and metals.

5 天之前 · Natural products play an important role in the management of oxidative stress-related diseases, as they can combat oxidative stress and reduce pathological complications associated with infectious diseases [16], [17].Rutin (3’,4’,5,7-tetrahydroxyflavone-3-rutinoside), also known as rutoside, is a flavonol glycoside with clinically relevant …