Oxidative Stress in Non-alcoholic Fatty Liver Disease. An Updated …
Different reactive oxygen species (ROS) generators contribute to NAFLD inflammatory and fibrotic progression, which is quite strictly linked to the lipotoxic liver injury from fatty acids and/or a …
Role of oxidative stress in the pathogenesis of nonalcoholic fatty ...
2020年5月20日 · Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common chronic liver disease worldwide and is strongly associated with the presence of oxidative …
Oxidative Stress Is a Key Modulator in the Development of …
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide, and scientific studies consistently report that NAFLD development can be accelerated by …
特别关注｜生物钟调控的线粒体动力学在非酒精性脂肪性肝病中的 …
2024年11月7日 · 氧化应激的特征是细胞内活性氧（ros）水平升高或还原能力减弱而产生的不可控氧化过程。哺乳动物的线粒体是产生ros的主要场所，氧化应激会损伤线粒体导致更多的ros产 …
Oxidative Stress as a Critical Factor in Nonalcoholic Fatty Liver ...
2017年4月1日 · Although augmented concentrations of ROS and faulty antioxidant defense have been associated to NAFLD and related complications, mechanisms of action and proofs of …
How cells flex their PEX to fine-tune lipolysis in NAFLD
2021年12月13日 · Investigating the role of peroxisomal ROS specifically in NAFLD promises potentially innovative therapeutic strategies to combat liver disease.
From mechanisms to medicine: Ferroptosis as a Therapeutic target …
2025年3月7日 · Particularly in NAFLD, iron deposition and oxidative stress, which arise from metabolic disorders, may induce ferroptosis, thereby promoting the progression of liver …
Therapeutic Nanomaterials in NAFLD: Current Advances and …
2024年12月4日 · Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic syndrome, encompassing a spectrum ranging from nonalcoholic fatty liver (NAFL) to …
Understanding lipotoxicity in NAFLD pathogenesis: is CD36 a
2020年9月25日 · Mitochondria are the most significant source of reactive oxygen species (ROS) in NAFLD, mainly due to increased fatty acid oxidation (FAO) upon FFAs overload 25. Briefly, …
MAM kinases: physiological roles, related diseases, and …
6 天之前 · Deficiency and abnormalities in Mfn2 expression underlie the pathogenesis of non-alcoholic fatty liver disease (NAFLD), T2DM, diabetic nephropathy, and Charcot–Marie–Tooth …
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