
RNF168 Gene - GeneCards | RN168 Protein | RN168 Antibody
2025年3月30日 · RNF168 (Ring Finger Protein 168) is a Protein Coding gene. Diseases associated with RNF168 include Riddle Syndrome and Digeorge Syndrome. Among its related …
NCB丨高大明组揭示mTOR影响基因组稳定性的分子机制—王平、 …
通过IR-免疫荧光、免疫组化染色、CSR(class-swith recombination)等实验,进一步验证了生理条件下,RNF168-S60磷酸化(RNF168-SE突变模拟磷酸化)后,小鼠的DNA损伤修复功能 …
Mechanisms of RNF168 nucleosome recognition and ubiquitylation
2024年1月18日 · RNF168 controls the chromatin recruitment of several DNA damage response (DDR) proteins, but its mechanisms of action remain unclear. Hu et al. unveil how RNF168 …
RNF168, a new RING finger, MIU-containing protein that modifies ...
2009年6月5日 · We identified and characterized RNF168, a new chromatin-associated RING finger protein. We demonstrated that RNF168 is endowed with ubiquitin ligase activity both in …
Emerging Roles of RNF168 in Tumor Progression - MDPI
2023年2月2日 · RING finger protein 168 (RNF168) is an E3 ubiquitin ligase with the RING finger domain. It is an important protein contributing to the DNA double-strand damage repair …
ZNF451 collaborates with RNF8 to regulate RNF168 localization …
2025年3月7日 · The ubiquitination of histone H2A/H2AX, catalyzed by RNF8/RNF168, is a crucial step in the repair of DNA double-strand breaks (DSBs), playing a significant role in transmitting …
165918 - Gene ResultRNF168 ring finger protein 168 [ (human)]
2025年2月19日 · RNF168 suppresses the cancer stem cell-like traits of nonsmall cell lung cancer cells by mediating RhoC ubiquitination. RNF168-mediated localization of BARD1 recruits the …
无名指蛋白 168(RNF168)基因 | MCE
该基因编码包含无名指的 E3 泛素连接酶蛋白,无名指是存在于多种功能不同的蛋白质中的基序,已知参与蛋白质-DNA 和蛋白质-蛋白质相互作用。 该蛋白质参与 DNA 双链断裂 (DSB) 修 …
RNF168 在肿瘤进展中的新作用。,Molecules - X-MOL
环指蛋白 168 (RNF168) 是一种具有环指结构域的 E3 泛素连接酶。 它是一种重要的蛋白质,有助于 DNA 双链损伤修复途径。 最近的研究发现RNF168与多种癌症的发生发展有显着关系。
RNF168 regulates R-loop resolution and genomic stability in
2021年2月1日 · We demonstrate that RNF168 deficiency resulted in accumulation of R-loops in BRCA1/2-mutant breast and ovarian cancer cells, leading to DSBs, senescence, and …