Ricin (/ ˈ r aɪ s ɪ n / RY-sin) is a lectin (a carbohydrate-binding protein) and a highly potent toxin produced in the seeds of the castor oil plant, Ricinus communis. The median lethal dose (LD …

The inhalation median lethal dose (LD50) is 3-5 µg/kg while the oral LD50 is 20 mg/kg. This difference may be due to the relatively large molecular size of RT and its degradation through …

Ricin’s lethal dose in humans was estimated to be about 1.78 mg for an average adult [21]. However, its toxicity depends on the route of exposure. Inhalation is more potent than oral …

2005年11月9日 · Ricin is a toxin derived from the castor bean plant Ricinus communis. Poisoning can occur via ingestion, inhalation, or injection. Ricin poisoning can have a presentation similar …

Ricin toxin is a highly toxic protein produced within the beans of the Ricinus communis (castor bean) plant. The median lethal dose (LD50) in mice is 5 micrograms per kilogram (μg/kg) body …

Recently, ricin has been shown to have an LD 50 of 29 mg/kg (ig), 0.023 mg/kg (ip), and 0.008 mg/kg (iv) [27]. Ebulin 1 has an LD 50 of 2.5 mg/kg (ip) and ebulin f has an oral LD 50 of 5...

Although it is conventional in inhalation toxicology to express lethal challenges as the concentration time product which kills 50% of the study population (LCt 50) , the lethal …

1 天前 · The median oral lethal doses (LD 50) of ricin and abrin for humans are 0.1–1 μg/kg and 0.01–0.04 μg/kg, respectively [7,8]. The structural similarities, high toxicity, and readily …

2021年1月1日 · When ricin is introduced through the intraperitoneal route, its LD 50 in mice is reported to range from 2.4 to 36 μg/kg (Worbs et al. 2011). On the other hand, intraperitoneal …

Oral administration of ricin was reported to give a lethal dose (LD) for 50% of animals (LD 50 s) 20 to 30 mg/kg in rat and 15 to 35 mg/kg in mouse [70,71,72]. For intravenous, inhalation and …