Retromer - Wikipedia
Retromer is a complex of proteins that has been shown to be important in recycling transmembrane receptors from endosomes to the trans -Golgi network (TGN) and directly …
Retromer: Current Biology - Cell Press
2017年7月24日 · What is retromer? Retromer is a protein coat that mediates endosomal protein sorting and trafficking. It assembles on endosomes and forms tubular vesicles that return …
北京大学生命科学学院 - pku.edu.cn
Retromer复合体是一个进化上高度保守的内体分选 (endocytic sorting) 复合体，主要介导跨膜蛋白从内体 (endosome) 到反式高尔基体网络或质膜的逆向囊泡运输。 之前的研究表明Retromer …
Journal of Cell Biology|杨崇林实验室揭示依赖于逆向蛋白运输复合体Retromer …
2022年10月4日 · 逆向蛋白运输复合体Retromer介导因细胞内吞或胞内运输而抵达内吞体的受体重新逆向回收到细胞膜或高尔基体，其缺陷与神经退行性疾病等多种人类疾病密切相关。 …
The retromer complex – endosomal protein recycling and beyond
The retromer complex is a vital element of the endosomal protein sorting machinery that is conserved across all eukaryotes. Retromer is most closely associated with the endosome-to …
Nature | 攻克癌症耐药新靶点：Retromer氧化状态有望成为治疗新 …
2025年3月30日 · 这表明，通过靶向调控Retromer复合物的氧化状态，特别是提高VPS35蛋白的氧化水平，可能是一种有效克服癌症耐药性的新策略。
Retromer promotes the lysosomal turnover of mtDNA - Science
The retromer promotes the formation of mitochondrial-derived vesicles shuttled to lysosomes. The mtDNA, however, directly shuttles to a recycling organelle in a BAX-dependent manner.
The Retromer Complex: From Genesis to Revelations
2021年7月1日 · In this review, the history of retromer is distilled into a concentrated form that spans the identification of retromer to recent discoveries that have shed new light on how …
Retromer 促进线粒体 DNA（mtDNA）的溶酶体周转：解锁线粒体 …
3 天之前 · Retromer 促进线粒体应激时线粒体基质成分的释放：有研究提出，Retromer 可能通过形成线粒体衍生小泡（MDVs）参与线粒体质量控制。 研究人员在实验中观察到，mtDNA 复 …
Retromer - an overview | ScienceDirect Topics
Retromer is an evolutionarily conserved multimeric protein complex that mediates intracellular transport of various vesicular cargoes and functions in a wide variety of cellular processes …