2025年3月30日 · RPS14 (Ribosomal Protein S14) is a Protein Coding gene. Diseases associated with RPS14 include Chromosome 5Q Deletion Syndrome and Protein-Deficiency Anemia. Among its related pathways are Peptide chain elongation and Nervous system development.

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is …

2025年1月4日 · Fine-structure map of the human ribosomal protein gene RPS14. Integrated analyses of translatome and proteome identify the rules of translation selectivity in RPS14-deficient cells.

40S ribosomal protein S14 is a protein that in humans is encoded by the RPS14 gene. [5] [6] [7] Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins.

The ribosomal protein S14 (RPS14) gene located at 5q33 codes for a protein involved in ribosomal biogenesis. The RPS14 gene has a length of 5.9 kb of DNA comprising 5 exons and 4 introns. It is possible that RPS14 is involved in the formation of pre-RNA 18s, an intermediate RNA that serves for the f …

2024年11月3日 · Title: Genome-wide functional integration identified MAZ-controlled RPS14 dysregulation in hepatocellular carcinoma. RPS14 promotes the development and progression of glioma via p53 signaling pathway.

Objectives: Ribosomal protein S14 (RPS14) plays a key role in erythropoiesis and causes p53 activation in 5q- syndrome. However, the oncogenic potential of RPS14 is not understood in leukemia and high-risk myelodysplastic syndrome (MDS).

lower RPS14 predicts prolonged survival and possible response to lenalidomide in lower risk MDS patients. RPS14 and RPS19 have distinct roles in regulating the MDM2-p53 feedback loop in response to ribosomal stress; Loss of RPS14 is associated with 5q-syndrome.

The RPS14 gene provides instructions for making one of approximately 80 different ribosomal proteins, which are components of cellular structures called ribosomes. Learn about this gene and related health conditions.

RPS14的详细信息，包括基因名称，代码，染色体位置，相互作用关系和通路，简述为核糖体，催化蛋白质合成的细胞器，由一个小40S亚基和60S大亚基。 一起这些亚基组成的4 RNA种类和大约80结构不同的蛋白质。 该基因编码一种核糖体蛋白，它是40S亚基的一个组成部分。 该蛋白属于S11P家族核糖体的蛋白质。 它位于细胞质中。 利用替代转录起始位点的转录变体在文献中已有描述。 作为典型编码核糖体蛋白的基因，有该基因通过基因组分散的多个经处理的假基因。 在 …