Anti-mitochondrial antibodies (AMA) have been reported in 90-96% of patients with primary biliary cirrhosis (PBC). AMA are also occasionally found in sera of patients with other liver conditions, including chronic active hepatitis, cryptogenic cirrhosis and in patients with clinical but no biochemical evidence of liver disease.

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This test looks for substances called antimitochondrial antibodies and antimitochondrial M2 antibodies in your blood. These substances are usually made by your body if you have a condition called primary biliary cirrhosis (PBC). PBC is the most common autoimmune disease that affects the …

AMA-M2 are highly specific for primary biliary cholangitis (PBC), formerly known as primary biliary cirrhosis (5, 6), a relatively uncommon chronic autoimmune disease resulting in progressive destruction of the intrahepatic biliary tree that can eventually lead to liver cirrhosis.

Anti-mitochondrial M2 antibody (AMA-M2) is specific to primary biliary cirrhosis (PBC), but can also be found in certain patients with autoimmune hepatitis (AIH). Effective methods of differentiating between PBC and AIH are required, as their …

Anti-mitochondrial antibodies (AMA) have been reported in the majority of patients with primary biliary cirrhosis (PBC). AMA are also occasionally found in sera of patients with other liver conditions, including chronic active hepatitis, cryptogenic cirrhosis and in patients with clinical but no biochemical evidence of liver disease.

Anti-Mitochondrial M2 Ab (RDL) UofM: Units: Result LOINC: 8077-0: Order Code: 520197: Order Code Name: Autoimmune Liver Profile (RDL) Order Loinc: 94700-2: Result Code: 520115: Result Code Name: Anti-Soluble Liver Ag Ab (RDL) UofM: Units: Result LOINC: 12734-0: Order Code: 520197: Order Code Name: Autoimmune Liver Profile (RDL) Order Loinc ...

What does it mean if your Mitochondrial (M2) Antibody result is too high? Antimitochondrial antibodies (AMA) have been reported in 90% to 96% of patients with primary biliary cirrhosis.

A positive result for antimitochondrial antibodies of M2 specificity in the setting of chronic cholestasis after exclusion of other causes of liver disease is highly suggestive of primary biliary cholangitis.

Anti-mitochondrial M2 antibodies enhance the risk of supraventricular arrhythmias in patients with elevated hepatobiliary enzyme levels. Intern Med 56: 1771-1779, 2017. [ DOI ] [ PMC free article ] [ PubMed ] [ Google Scholar ]