About Mutations in the RAD51C Gene - Memorial Sloan Kettering Cancer Center
2023年7月17日 · A RAD51C mutation increases your risk for ovarian cancer. A RAD51C mutation may also increase your risk for breast cancer, but more research is needed for us to better …
RAD51C - Wikipedia
RAD51 homolog C (S. cerevisiae), also known as RAD51C, is a protein which in humans is encoded by the RAD51C gene. [5][6] The RAD51C protein is one of five paralogs of RAD51, …
实力靶点RAD51：损伤修复，不辨不明 - 知乎
基于DNA损伤修复原理在PARP上取得的成功以及PARP抑制剂耐药的出现，一些相关靶点RAD51、Wee1、ATM、ATR、PRMT5等也引起了研发人员的极大热情，成为近年来的热门 …
RAD51C Gene - GeneCards | RA51C Protein | RA51C Antibody
2025年3月30日 · RAD51C (RAD51 Paralog C) is a Protein Coding gene. Diseases associated with RAD51C include Breast-Ovarian Cancer, Familial 3 and Fanconi Anemia, …
RAD51C 基因突变会增加罹患卵巢癌的⻛ 险。 RAD51C 突变也可能会增加罹患乳腺癌的⻛险, 但我们还需要进行 更多研究才能更好地了解这种⻛ 险。 虽然 RAD51C 基因突变意味着罹患癌 …
Cancer Risk in People with a RAD51C Mutation
2025年3月25日 · Women with a RAD51C mutation have about a 10-15 percent lifetime risk for ovarian, fallopian tube or primary peritoneal cancer (these three cancers and their risks are …
RAD51C-XRCC3 structure and cancer patient mutations define …
2023年7月24日 · Here we report the RAD51C-XRCC3 (CX3) X-ray co-crystal structure with bound ATP analog and define separable RAD51C replication stability roles informed by its three …
Abnormal expression of Rad51C, which is a key factor in the HR pathway, may result in DNA repair disorder, genomic instability, and eventually lead to tumor formation. In recent studies, …
5889 - Gene ResultRAD51C RAD51 paralog C [ (human)]
RAD51C is a rare breast and ovarian cancer susceptibility gene. PALB2 mutations are present in a small but substantial proportion of inherited breast cancer cases, and indicates that RAD51C …
RAD51C Gene Mutations: Risk, Management and Treatment
2025年3月25日 · Expert guidelines include recommendations for people with RAD51C mutations on managing their cancer risk. People with a RAD51C mutation who have been diagnosed …