Rutin (rutoside, quercetin-3-O-rutinoside or sophorin) is the glycoside combining the flavonol quercetin and the disaccharide rutinose (α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranose). It is a flavonoid glycoside found in a wide variety of plants, including citrus.

Rutin is a rutinoside that is quercetin with the hydroxy group at position C-3 substituted with glucose and rhamnose sugar groups. It has a role as a metabolite and an antioxidant. It is a disaccharide derivative, a quercetin O-glucoside, a tetrahydroxyflavone and a rutinoside.

Rutin, also called as rutoside, quercetin-3-rutinoside, and sophorin is a citrus flavonoid glycoside found in buckwheat (Kreft et al., 1997). The name ‘rutin’ comes from the plant Ruta graveolens , which also contains rutin.

Collectively, results from this study suggest that the quercetin 3-O-rutinoside has the capability to inhibit PBP2a and hence could be used as an alternative or in combination with other drugs in treating MRSA infection.

2024年1月4日 · Chemsrc provides Quercetin 3-O-rutinoside (CAS#:949926-49-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Quercetin 3-O-rutinoside are included as well.

Rutin (rutoside or quercetin-3-O-rutinoside) is a flavonoid contained in many plants. The major sources of rutin for medical use include buckwheat, Japanese pagoda tree, and Eucalyptus macrorhyncha.

Rutin, or Quercetrin-3-rutinoside, was found to inhibit both in vivo and in vitro formation of blood clots in thrombosis by blocking the enzyme disulfide isomerase (PDI), an essential component in the development of this disease.

Our results demonstrate that rutin isolated from M. oleifera significantly alleviates lipid content and adipogenesis, and improves glucose uptake through regulating PPAR-γ and AMPK signaling pathways; thus, rutin can be considered as a potential therapeutic agent against adiposity and glucose intolerance.

Purpose: In this study, we aim to establish the gastroprotective role of flavonoid, Quercetin-3-O-rutinoside (Q-3-R) against 7.5 Gy total body gamma radiation dose that contributes to the hematopoietic syndrome.

2023年2月1日 · In the present study, we demonstrate that Quercetin- 3-O- Rutinoside or Q-3-R, a polyphenol with diverse pharmacological properties prevents radiation mediated GI injury by differential regulation of key signaling mediators involved in …

Rutin (quercetin-3-rutinoside) modulates the hemostatic disturbances and redox imbalance induced by Bothrops jararaca snake venom in mice. ... In fact, the values of the area under the curve (AUC) for ROC curves between DCF (0.728 ± 0.063; cutoff 1.3) or TAC (0.618 ± 0.072; cutoff 1.1) and platelet counts were modestly high, and thereby they ...

Rutin (Rutoside) is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin is also a CBR1 inhibitor, which can cross the blood brain barrier.

2014年5月31日 · It is also known as vitamin P and quercetin-3-O-rutinoside. In addition, it is found in many food items, vegetables, and beverages. The cytoprotective effects of rutin, including gastroprotective, hepatoprotective, and anti-diabetic effects, have been shown in several studies.

2023年2月13日 · Our results demonstrate that rutin isolated from M. oleifera significantly alleviates lipid content and adipogenesis, and improves glucose uptake through regulating PPAR-γ and AMPK signaling pathways; thus, rutin can be considered as a potential therapeutic agent against adiposity and glucose intolerance.

Unprecedentedly, the metabolic pathway of the major phenolic compound quercetin-3- O -rutinose-7- O -α-L-rhamnoside by L. plantarum, appeared to be the direct fission of C-ring at C2–O1 and C3–C4 bonds, which was proved from the occurrence of two substances with the deprotonated molecule [M–H] − ion at m/z 299 and 459, respectively.

2023年4月1日 · In this study, we aim to establish the gastroprotective role of flavonoid, Quercetin-3-O-rutinoside (Q-3-R) against 7.5 Gy total body gamma radiation dose that contributes to the hematopoietic syndrome.

Rutin, also termed rutoside, quercetin-3-O-rutinoside, and sophorin, is the glycoside composed of flavonol quercetin and disaccharide rutinose (Fig. 12). Rutin is one of the major polyphenolic components of tobacco.

Collectively, results from this study suggest that the quercetin 3-O-rutinoside has the capability to inhibit PBP2a and hence could be used as an alternative or in combination with other drugs in treating MRSA infection.

2025年2月24日 · Quercetagetin, 3, 5, 6, 7, 3′, 4′-Hexahydroxy-flavone (Que), is a yellow flavonol with an extra OH at C-6 in ring A related to the common 5,7-OH-type ring A flavonol quercetin. The related research about Que over the last 20 years has been obviously increased. This study delves into the research progress of Que: occurrence, chemical and biosynthesis pathways, …

We present here a novel biocatalytic methodology for the preparation of quercetin from plant-derived rutin, with both substrate and product being in mostly an undissolved state during biotransformation.

2022年5月1日 · Among the polyphenolic group members, Quercetin (3,3′,4′,5,7-pentahydroxyflavone) (Q) is one of the most studied flavonoid due to its activities in reduction of inflammation, oxidative damage, platelet aggregation, and capillary permeability.

5 天之前 · The results indicate that the protein in complex with quercetin and UDP displays lower RMSD values (2.26 ± 0.19 Å) than in its apo form (2.82 ± 0.33 Å), suggesting greater conformational ...