Pinner first proposed the name “pyrimidin” in 1885. [9] The parent compound was first prepared by Gabriel and Colman in 1900, [10] [11] by conversion of barbituric acid to 2,4,6-trichloropyrimidine followed by reduction using zinc dust in hot water.

形成DNA和RNA的五种 碱基 中，有三种是嘧啶的衍生物： 胞嘧啶 （Cytosine）， 胸腺嘧啶 （Thymine）， 尿嘧啶 （Uracil）其中胸腺嘧啶只能出现在脱氧 核糖 核酸中，尿嘧啶只能出现在 核糖核酸 中，而胞嘧啶两者均可。 在 碱基互补配对 时，胸腺嘧啶（DNA中）或尿嘧啶（RNA中）与腺 嘌呤 以2个氢键结合 ...

Pyrimidine | C4H4N2 | CID 9260 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety ...

pyrimidine，英语单词，主要用作名词，作名词时译为“嘧啶，密定二氮三烯陆环”。

2015年5月20日 · The importance of pyrimidines lies in the fact that they are structural components of a broad spectrum of key molecules that participate in diverse cellular functions, such as synthesis of DNA, RNA, lipids, and carbohydrates. Pyrimidine metabolism encompasses all enzymes involved in the synthesis, d …

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Pyrimidine salt such as 4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl ammonium-2,5-dichloro-4-hydroxy-3,6-dioxo-cyclohexa-1,4-dienolate (47) chloranilic acid was synthesized and screened for in vitro antibacterial activity.

2023年8月3日 · Pyrimidine is a class of organic heterocyclic compounds containing 2 nitrogen atoms in their carbon ring. Pyrimidines are defined as polyunsaturated six-membered aromatic heterocyclic compounds containing two nitrogen atoms at the 1, 3 – position of the ring.

2015年6月5日 · A one-pot synthesis of 1-benzoyl-2(S)-substituted-5-iodo-2,3-dihydro pyrimidin-4(1H)-ones was developed, based on the tandem decarboxylation b-iodination of 6-carboxyhexahydropyrimidin-4-one and these were processed further to give α-substituted b-amino acids with high enantioselectivity like (a-c) (Diaz-Sanchez et al., 2007).

N-methyl-N-pyrimidin-2-yl glycine and N-5H-[1]benzopyrano[4,3-d]pyrimidin-2-yl (IV) substituted amino acids and tested for anti-inflammatory activity. All the compounds showed significant anti-inflammatory activity. Sacchi et al[19] synthesized a series of imidazo[1,2-a] pyrimidine 2-carboxylic acid and