Mar 30, 2025 · PSG3 (Pregnancy Specific Beta-1-Glycoprotein 3) is a Protein Coding gene. Diseases associated with PSG3 include Gestational Choriocarcinoma and Rh Isoimmunization . Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Cell surface interactions at the vascular wall .

人类妊娠特异性糖蛋白（PSGs）是一家族在妊娠期间由胎盘滋养层细胞大量合成并释放到母体循环中的蛋白质。 几个PSG基因的分子克隆和分析表明，PSGs构成了癌胚抗原（CEA）基因家族的子群，属于免疫球蛋白超家族基因。 CEA家族的成员包括一个与免疫球蛋白可变结构域结构相似的单一N结构域，后面是一个可变数量的免疫球蛋白恒定样A和/或B结构域。 大多数PSG具有精-甘-天冬（RGD）基序，该基序已被证明在N端结构域中作为几个整合素的粘附识别信号发挥作 …

Nov 14, 2024 · Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes.

人类妊娠特异性糖蛋白 (PSG) 是一个由胎盘滋养细胞大量合成并在妊娠期间释放到母体循环中的蛋白质家族。 几个 PSG 基因的分子克隆和分析表明，PSG 形成癌胚抗原 (CEA) 基因家族的一个亚组，属于免疫球蛋白基因超家族。 CEA 家族的成员由一个 N 结构域组成，其结构与免疫球蛋白可变结构域相似，随后是数量可变的免疫球蛋白恒定样 A 和/或 B 结构域。 大多数 PSG 具有 arg-gly-asp (RGD) 基序，它已被证明在 N 末端结构域中充当多种整合素的粘附识别信号 (Teglund 等人 …

Pregnancy-specific beta-1-glycoprotein 3 is a protein that in humans is encoded by the PSG3 gene. [3] [4]

pregnancy-specific beta-1-glycoprotein 3, PS-beta-G-3, PSBG-3, carcinoembryonic antigen SG5, pregnancy-specific glycoprotein 3. The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy.

Apr 1, 2010 · The PSG3 promoter region (−251/−49) was subcloned from PB3-luc by restriction deletion to create UB3-luc, and NB3-luc (−178/−49 of PSG3 promoter) was obtained through PCR amplification, restriction digestion and subcloning into pGL3-basic. mRARE PB3-luc and mGABP PB3-luc are derivative mutants of PB3-luc obtained by PCR-directed ...

Feb 8, 2025 · Clinical resource with information about PSG3, and available tests. There are links to practice guidelines and authoritative resources like GeneReviews, PubMed, MedlinePlus, PharmGKB and clinicaltrials.gov.

RNA specificity category based on RNA sequencing data from cancer cell lines in the Human Protein Atlas grouped according to type of cancer. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.

Jun 13, 2006 · Showing features for natural variant. We now provide the "Disease & Variants" viewer in its own tab. The viewer provides 912 variants from UniProt as well as other sources including ClinVar and dbSNP. Go to variant viewer. Showing features for signal, chain, glycosylation, disulfide bond. PSBG are produced in high quantity during pregnancy. Search…