Prostaglandin H2 is an unstable intermediate produced from arachidonic acid through a two-step conversion catalyzed by cyclooxygenase (COX). It is further metabolized into more stable metabolites, including PGE2, PGD2, PGF2, PGI2, and thromboxane A2.

Prostaglandin H2 is an oxylipin, an olefinic compound, a secondary alcohol and a prostaglandins H. It has a role as a mouse metabolite. It is a conjugate acid of a prostaglandin H2 (1-). Prostaglandin h2 has been reported in Homo sapiens with data available.

Prostaglandin H2 is a vasoactive molecule produced from arachidonic acid by the enzyme prostaglandin H2 synthase. It plays a role in mediating vascular functions and can interact with receptors in vascular smooth muscle cells to induce vasoconstriction.

The prostaglandin intermediate, prostaglandin H 2 (PGH 2), is produced by cyclooxygenase as a precursor for other prostaglandins and for the thromboxanes (Fig. 11-20). PGH 2 contains a cyclopentane ring formed by action of cyclooxygenase.

Prostaglandins are natural and powerful substances that affect several aspects of your body. While prostaglandins are necessary for bodily processes such as healing, having excess prostaglandins can cause chronic pain and inflammation and lower your quality of life.

2001年10月12日 · Prostaglandin H synthase (PGHS) is a rate-limiting enzyme in the production of prostaglandins and thromboxane, which are important regulators of vascular function. Under normal physiological conditions, PGHS-dependent vasodilators (such as …

Prostaglandin H2: 2-<wbr/>series PGs and thromboxane precursor. CAS Number: 42935-17-1. Synonym: PGH2. Purity: ≥95%.

Anti-peptide antibodies against the human blood platelet thromboxane A2/prostaglandin H2 receptor. Production, purification and characterization.

2004年1月9日 · Prostaglandin H2 synthase (EC 1.14.99.1) is an integral membrane enzyme containing a cyclooxygenase site, which is the target for the non-steroidal anti-inflammatory drugs, and a spatially distinct peroxidase site.

1994年1月20日 · The three-dimensional structure of prostaglandin H2 synthase-1, an integral membrane protein, has been determined at 3.5 A resolution by X-ray crystallography. This bifunctional enzyme comprises three independent folding units: an epidermal growth factor domain, a membrane-binding motif and an enzym …