In organic chemistry, polyenes are poly-unsaturated, organic compounds that contain at least three alternating double (C=C) and single (C−C) carbon–carbon bonds. These carbon–carbon double bonds interact in a process known as conjugation, resulting in …

polyene， 英语单词，主要用作 名词，作名词时译为“ [有化] 多烯”。 [1] n. [有化] 多烯 [1] The use of macrolide polyene antibiotics or derivatives or analogues thereof as culture supplement for the propagation of virus is described. 本发明描述了大环内酯多烯抗生素或其衍生物或类似物作为培养物补充物用于病毒繁殖的用途。

Polyunsaturated alkenes, or polyenes, are compounds that have several carbon-carbon double bonds. The double bonds can be spaced out along the carbon chain, with several carbon-carbon single bonds separating them.

Polyenes are a group of antifungal drugs with multiple conjugated double bonds and a heavily hydroxylated region on the ring opposite to the conjugated system. These are amphiphilic and act by binding to sterols (primarily ergosterol) present in the fungal cell membrane.

2018年7月22日 · Polyenes are formally defined as materials containing an even number of methyne (=CH–) groups covalently bonded to form a linear carbon chain bearing one p electron on each carbon atom [3,4,5,6]. As such, the chemical structure of polyenes is best represented by a formula R–(CH=CH) n –R, where n denotes the number of repeating units and R ...

Polyenes are poly-unsaturated organic compounds that contain one or more sequences of alternating double and single carbon-carbon bonds. These double carbon-carbon bonds interact in a process known as conjugation, which results in an overall lower energy state of the molecule.

ABLC是脂质体与两性霉素B交织而成的药物，能迅速被网状内皮细胞摄取而减少与蛋白质的结合，改善两性霉素B体内过程和毒理学特性，最大限度地降低毒副作用。 ABLC对多种深部真菌具有很强的活性，可用于中性粒细胞减少症和发热患者的经验性疗法 [5]。 ABLC是剂量依赖型药物，对于治疗中枢神经系统曲霉菌也很有效，与卡泊芬净联用治疗原因不明的发热病症，效果明显。 ABCD在欧洲和美国广泛用于临床，是由胆固醇硫酸酯与等量的两性霉素B混合包裹而成，对 …

What are Polyenes? Antifungal agents are also called antimycotic agents. Polyene antifungals bind to ergosterol, the main sterol in the fungal cell membrane, and cause depolarization of the membrane.

2025年3月10日 · Polyenes with an extensively cross-conjugated backbone, namely poly (1,1-vinylene)s or dendralenes, have fascinated chemists owing to their unique opto-electronic properties and reactivities....

Discover the fascinating world of polyenes, a significant group of compounds in the field of microbiology. Unpack their definition, understand their structural formation, explore various examples and most importantly, how these elements operate within a biological context.