A podocyte has a complex structure. Its cell body has extending major or primary processes that form secondary processes as podocyte foot processes or pedicels. [6]

足细胞（podocyte），即肾小囊脏层上皮细胞，它附着于肾小球基底膜（GBM）的外侧，连同血管内皮细胞和肾小球基膜一起构成了肾小球血液滤过屏障。

足細胞 （podocyte 、或"內臟上皮細胞" (visceral epithelial cell)）為位於 腎臟 鮑氏囊 上環繞着 腎小球 毛細血管之細胞。 [1] 鮑氏囊過濾血液，阻礙大分子，如 蛋白質 、 紅血球 、 血小板； …

In this review, we take a membrane biologist’s view of the podocyte, examining the many membrane receptors, channels, and other signaling molecules that have been implicated in …

In the following sections, we outline the response of podocytes to various stimuli or injury (or both) to better understand the mechanisms underlying podocyte FP effacement, proteinuria, and …

2016年1月28日 · The genetic or acquired impairment of podocytes may lead to foot process effacement (podocyte fusion or retraction), a morphological hallmark of proteinuric renal …

2016年8月30日 · This Review outlines the role of actin dynamics and endocytosis in podocyte biology, and discusses how molecular heterogeneity in glomerular disorders could be …

Podocyte injury in response to stress causes their detachment from the glomerular basement membrane, followed by proteinuria and progressive renal failure. A review on the state of the …

2024年3月5日 · Throughout the past two decades, a holistic picture of podocyte cell biology has emerged, highlighting mechanobiological signalling pathways, cytoskeletal dynamics and …

The podocyte is partly responsible for the synthesis and turnover of the GBM, and podocyte-derived growth factors, particularly VEGF, are critical to the endothelial function.