2025年3月30日 · PLIN2 (Perilipin 2) is a Protein Coding gene. Diseases associated with PLIN2 include Sebaceous Adenocarcinoma and Meibomian Cyst. Among its related pathways are …

Adipose differentiation-related protein, also known as perilipin 2, ADRP or adipophilin, is a protein which belongs to the perilipin (PAT) family of cytoplasmic lipid droplet (CLD)–binding proteins. …

Overexpression or suppression of PLIN2 can enhance or inhibit tumor cell migration, invasion, and vascular permeability in vitro, which is also confirmed in vivo. Mechanistically, it is …

2025年2月7日 · PLIN2, a marker of macrophage LDs, is essential for cell survival under hypoxia and its expression can be stimulated by HIF1α in post-ischemic brain injury. However, the …

2022年5月25日 · Upon exit from pluripotency, lipid droplet (LD)-associated protein Plin2 is recognized by Hsc70 and degraded via chaperone-mediated autophagy to facilitate LD …

2023年9月25日 · Despite the key roles of perilipin-2 (PLIN2) in governing lipid droplet (LD) metabolism, the mechanisms that regulate PLIN2 levels remain incompletely understood. …

由该基因编码的蛋白质属于 perilipin 家族，其成员覆盖细胞内脂质储存液滴。 这种蛋白质与脂质球表面膜物质有关，可能参与脂肪组织的发育和维持。 然而，它并不像以前认为的那样仅限于 …

2023年5月8日 · Our findings reveal the critical regulation of PLIN2 -induced ectopic lipid accumulation in phase-related muscle ageing plasticity. We initially determined the lifespan …

Perilipin2 (PLIN2)，又称脂肪分化相关蛋白(ADRP)，参与协助中性脂质在脂滴内的储存。有研究报道，PLIN2在胃癌组织中呈现出显著的过表达。然而，对于PLIN2如何通过脂质代谢失衡来诱 …

2017年7月3日 · Of the corresponding gene products, PLIN2 is the only constitutive and ubiquitously expressed lipid droplet protein that has been used as a protein marker for lipid …