A plexin is a protein which acts as a receptor for semaphorin family signaling proteins. [1] [2] [3] It is classically known for its expression on the surface of axon growth cones and involvement in …

2020年5月6日 · Plexin家族蛋白是一种单次跨膜蛋白，由Plexin A (1-4), Plexin B (1-3), Plexin C1, Plexin D1四个亚家族组成，它们是神经引导分子（neuronal guidance molecule）Semaphorin …

2014年8月1日 · Several semaphorins and plexins are critically involved in tumour growth and metastasis by controlling tumour development and progression via the formation of autocrine …

导向受体神经丛蛋白plexins是在轴突引导、肿瘤进展和免疫细胞调节中具有一系列重要功能的一类细胞受体。 已知plexins主要通过与配体（semaphorin ligands）结合，以结合细胞或游离状态 …

2019年2月13日 · Plexins and semaphorins are cell surface receptors and ligands that regulate multiple processes of development and adult physiology, including neural development, …

2025年2月1日 · Plexins are vital transmembrane receptors in nervous system development. Plexins are essential for neural development, axon guidance, and cell migration. There are …

Class A plexins (PlxnAs) act as semaphorin receptors and control diverse aspects of nervous system development and plasticity, ranging from axon guidance and neuron migration to …

Signaling through plexin, the major cell surface receptor for semaphorin, plays critical roles in regulating processes such as neuronal axon guidance, angiogenesis and immune response. …

A Plexin is a type of transmembrane protein found in cells, characterized by the presence of a Sema domain at their N-terminus, a cysteine-rich motif in their extracellular region, and a …

1999年10月1日 · We find that the two known semaphorin-binding proteins, plexin 1 (Plex 1) and neuropilin-1 (NP-1), form a stable complex. Plex 1 alone does not bind semaphorin-3A …