Feb 1, 2024 · PhoU is a negative regulator for the Pi-responsive PhoB/PhoR two-component system. PhoU controls responses to phosphate and its counterions, such as Mg 2+ and K +. …

Nov 23, 2023 · This review discusses the multifaceted functions of the PhoU protein in bacterial regulation, focusing on its role in coordinating Pi transport with counterions, controlling …

Dec 11, 2024 · PhoU proteins are negative regulators of the phosphate response, regulate virulence, and contribute to antibiotic resistance. Staphylococcus aureus has multiple genes …

Nov 1, 2017 · Phosphate control of the biosynthesis of secondary metabolites in Streptomyces is mediated by the two component system PhoR–PhoP. Linked to the phoR–phoP cluster, and …

May 26, 2020 · PhoU homologs are one of the determinant factors in the regulation of persister formation and phosphate metabolism in many bacterial species; however, the functions of …

In Escherichia coli, we identified a new persistence gene, phoU, whose inactivation leads to a generalized higher susceptibility than that of the parent strain to a diverse range of antibiotics, …

链霉菌次生代谢物生物合成的磷酸盐控制是由双组分系统 PhoR-PhoP 介导的。 与 phoR-phoP 簇相连并以相反方向表达的 phoU 样编码基因与大肠杆菌的 phoU 基因具有较低的同一性。 该 …

PhoU 连同高亲和力、Pi 特异性 ATP 结合盒转运蛋白 PstSCAB 和双组分蛋白 PhoR 和 PhoB，对于大肠杆菌中的 Pi 信号传导是绝对必需的。 关于 PhoU 的作用及其在调节中的功能知之甚少。

Maintenance of cellular phosphate homeostasis is essential for cellular life. The PhoU protein has emerged as a key regulator of this process in bacteria, and it is suggested to modulate …

Apr 1, 2010 · Our latest studies show that P i signaling involves three distinct processes, which appear to correspond to different states of the sensory histidine kinase PhoR: an inhibition …