PHGDH antibody (81986-1-RR) | Proteintech | 武汉三鹰生物技术 …
Proteintech's Rabbit Recombinant PHGDH antibody is validated in WB, IP, IHC, ELISA and shows reactivity with Human, mouse, rat samples.
PHGDH antibody (14719-1-AP) | Proteintech - ptglab
14719-1-AP targets PHGDH in WB, IHC, IF/ICC, IP, CoIP, RIP, ELISA applications and shows reactivity with human, mouse, rat samples. PBS with 0.02% sodium azide and 50% glycerol …
Phosphoglycerate dehydrogenase activates PKM2 to …
2023年3月10日 · During senescence, the expression of serine biosynthetic enzyme PHGDH is significantly reduced due to decreased transcription of the activating transcription factor ATF4, …
Interaction of PHGDH with IGF2BP1 facilitates m6A-dependent
3 天之前 · After transduction of truncated IGF2BP1 constructs together with full-length PHGDH, co-IP showed that the KH1/2 domains of IGF2BP1 were required for its interaction with …
Nature丨打破惯有认知，代谢酶PHGDH异质性或决定癌细胞转移 …
PHGDH 是丝氨酸合成通路中的关键酶，编码这种酶的基因在三阴性乳腺癌（TNBCs）、黑色素瘤等肿瘤中高表达。 研究人员发现，异质性/低表达PHGDH浸润性乳腺导管癌患者的中位无进展 …
RFWD3 Reprograms Nucleotide Metabolism Through PHGDH to …
2025年2月28日 · Mechanistically, RFWD3 bound to and ubiquitinated PHGDH at the Lys137 residue, promoting its degradation and conserving cellular oxidized nicotinamide adenine …
专访余秋景教授丨PHGDH基因与丝氨酸代谢功能新发现 - 知乎
我们进一步研究发现通过基因水平敲低PHGDH或用抑制剂CBR-5884抑制PHGDH活性，以及限制外源性丝氨酸和甘氨酸的摄取，均可以增强IFN-β介导的体内外抗病毒先天免疫。
PHGDH/SYK: a hub integrating anti-fungal immunity and serine
2024年9月10日 · The results of coimmunoprecipitation (Co-IP) and reverse Co-IP assays showed that Flag-tagged PHGDH specifically interacts with Myc-tagged SYK but not with HA-tagged …
PHGDH antibody (67591-1-PBS) | Proteintech | 武汉三鹰生物技术 …
IP result of anti-PHGDH (IP:67591-1-Ig, 4ug; Detection:67591-1-Ig 1:3000) with HeLa cells lysate 980 ug. This data was developed using the same antibody clone with 67591-1-PBS in a …
Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 14719-1-AP (PHGDH antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval …