
PFKFB2 Gene - GeneCards | F262 Protein | F262 Antibody
2025年3月30日 · PFKFB2 (6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 2) is a Protein Coding gene. Diseases associated with PFKFB2 include Breast Lipoma and Maturity-Onset …
Nature Metabolism丨PFKFB2 介导的糖酵解促进巨噬细胞乳酸驱动 …
We found that efferocytosis promotes a transient increase in macrophage glycolysis that is dependent on rapid activation of the enzyme 6-phosphofructo-2-kinase/fructose-2,6 …
PFKFB2-mediated glycolysis promotes lactate-driven continual
2023年2月16日 · We found that efferocytosis promotes a transient increase in macrophage glycolysis that is dependent on rapid activation of the enzyme 6-phosphofructo-2 …
PFKFB2 - Wikipedia
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 is an enzyme that in humans is encoded by the PFKFB2 gene. [5] The protein encoded by this gene is involved in both the synthesis …
6-磷酸果糖-2-激酶/果糖-2,6-双磷酸酶 2(PFKFB2)基因 | MCE
Broad expression in thyroid (RPKM 25.6), duodenum (RPKM 11.7) and 19 other tissues. 该基因编码的蛋白质参与果糖-2,6-二磷酸的合成和降解,果糖是一种控制真核生物糖酵解的调节分子。 …
Loss of Cardiac PFKFB2 Drives Metabolic, Functional, and ...
2024年3月27日 · PFKFB2, the cardiac isoform of PFK‐2, is degraded in the heart in the absence of insulin signaling, contributing to diabetes‐induced cardiac metabolic inflexibility. However, …
Pfkfb (6-phosphofructo-2-kinase/fructose-2,6 ... - ScienceDirect
2013年10月1日 · Pfkfb (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) enzymes are bi-functional enzymes encoded by four different genes (pfkfb1, pfkfb2, pfkfb3, pfkfb4) in …
Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
2025年2月8日 · Gene ID: 18640, updated on 8-Feb-2025. Enables 6-phosphofructo-2-kinase activity and fructose-2,6-bisphosphate 2-phosphatase activity. Predicted to be involved in …
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PFKFB2 regulates glycolysis and proliferation in pancreatic cancer cells. This study aims to characterise the expression and phosphorylation of isozymes of the key glycolytic regulatory …
2024年12月25日 · There are four PFKFB isoforms 2. In the heart, PFKFB2 is the primary isoform and its kinase activity is enhanced by protein phosphorylation by either Akt, AMPK, or PKA 1. …